成人尿便失禁的预防。

Tatyana Shamliyan, Jean Wyman, Donna Z Bliss, Robert L Kane, Timothy J Wilt
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引用次数: 0

摘要

目的:评估长期护理(LTC)和社区成人尿失禁(UI)和粪失禁(FI)的患病率和危险因素,诊断方法识别有尿失禁风险的成人和尿失禁患者的有效性,并回顾临床干预措施降低尿失禁风险的有效性。数据来源:MEDLINE (PubMed)、CINAHL和Cochrane数据库。回顾方法:回顾观察性研究,以检查UI和FI的患病率和发病率及其与危险因素的关系。从随机对照和多中心临床试验中分析治疗对患者预后的影响。比较了不同设计的原始流行病学研究的诊断价值。在鉴定的6097篇文章中,有1077篇文章符合分析条件。结果:尿失禁、尿失禁和合并尿失禁的患病率随着年龄和功能依赖的增加而增加。认知障碍、日常活动限制和长期住在养老院与尿失禁的高风险相关。在社区居住的成年人中,中风、糖尿病、肥胖、一般健康状况不佳和合并症与UI和FI相关。女性的胎次、肛门创伤和阴道脱垂以及男性的泌尿外科手术和前列腺癌放疗是UI和FI的危险因素。强化的个体化管理和康复计划改善了养老院居民和成人中风后的自理状况。自我管理行为干预包括骨盆底肌肉训练与生物反馈和膀胱训练解决尿失禁妇女尿失禁。电刺激和骶神经调节可改善急迫性UI,但对FI的改善不一致。无张力阴道胶带手术和改良手术技术脱垂,以支持膀胱颈部解决压力性尿失禁在大多数接受治疗的妇女。FI的行为治疗导致与尿失禁相关的严重程度和生活质量的小幅改善。痔疮、直肠脱垂、直肠癌和肛裂手术技术对FI的影响在各研究中并不一致。溃疡性结肠炎患者的手术干预导致相同的大便失禁率,彼此比较。在精心设计的试验中,少数治疗FI的临床干预措施没有明确的证据表明比较治疗的效果更好。评估治疗效果的工具结果与患者结果无关。与专业检查和诊断测试相比,用于检测高危人群和未确诊的尿失尿患者的流行病学调查具有相同的诊断价值,而且费用更低。自我报告的问卷和量表诊断FI的效度不理想。结论:流行病学调查是一种经济有效的方法,可用于估计具有全国代表性的大型人群中尿失禁的患病率。常规临床评估应包括对尿失禁的危险因素、症状和体征的评估。孕妇或更年期妇女、阴道脱垂的妇女、接受过前列腺疾病治疗的男性、直肠脱垂的患者、体弱的老年人和养老院的居民都是高危人群。个性化管理方案可以改善LTC设施的自理能力,但难以维持。定期监测和记录与实施的失禁服务有关的失禁状况应成为养老院的护理质量指标。骨盆底肌肉训练与生物反馈可以解决尿失禁和提高生活质量。手术是治疗女性应激性尿失禁的有效方法。男性尿失禁和成人FI的临床干预措施需要进一步研究。提供了一份研究建议清单。
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Prevention of urinary and fecal incontinence in adults.

Objectives: To assess the prevalence of and risk factors for urinary (UI) and fecal (FI) incontinence in adults in long-term care (LTC) settings and in the community, the effectiveness of diagnostic methods to identify adults at risk and patients with incontinence, and to review the effectiveness of clinical interventions to reduce the risk of incontinence.

Data sources: MEDLINE (PubMed), CINAHL, and Cochrane Databases.

Review methods: Observational studies were reviewed to examine the prevalence and incidence of UI and FI and the association with risk factors. The effects of treatments on patient outcomes were analyzed from randomized controlled and multicenter clinical trials. The diagnostic values of the tests were compared from the original epidemiologic studies of different designs. Of the 6,097 articles identified, 1,077 articles were eligible for analysis.

Results: The prevalence of UI, FI, and combined incontinence increased with age and functional dependency. Cognitive impairment, limitations in daily activities, and prolonged institutionalization in nursing homes were associated with a higher risk of incontinence. Stroke, diabetes, obesity, poor general health, and comorbidities were associated with UI and FI in community dwelling adults. Parity, anal trauma, and vaginal prolapse in women and urological surgery and radiation for prostate cancer in men are risk factors for UI and FI. Intensive individualized management and rehabilitation programs improved continence status in nursing home residents and adults after stroke. Self-administered behavioral interventions including pelvic floor muscle training with biofeedback and bladder training resolved UI in incontinent women. Electrical stimulation and sacral neuromodulation improved urge UI, but improvement for FI was inconsistent. Tension-free vaginal tape procedures and modified surgical techniques for prolapse to support the bladder neck resolved stress UI in the majority of treated women. Behavioral treatments of FI resulted in small improvements in severity and quality of life related to incontinence. The effects on FI of surgical techniques for hemorrhoids, rectal prolapse, rectal cancer, and anal fissures are not consistent across studies. Surgical interventions in patients with ulcerative colitis resulted in the same rates of fecal continence when compared to each other. The few clinical interventions to treat FI that were tested in well-designed trials had no clear evidence of better effects of the compared treatments. Instrumental outcomes to evaluate the effectiveness of treatments did not correlate with patient outcomes. Epidemiologic surveys to detect persons at risk and patients with undiagnosed UI have the same diagnostic value and less cost compared to professional examinations and diagnostic tests. Self-reported questionnaires and scales have unsatisfactory validity to diagnose FI.

Conclusions: Epidemiologic surveys are cost-effective ways to estimate the prevalence of UI in large nationally representative population groups. Routine clinical evaluation should include an assessment of the risk factors, symptoms, and signs of incontinence. Pregnant or menopausal women, women with vaginal prolapse, males treated for prostate disease, patients with rectal prolapse, and frail elderly and nursing home residents are high risk groups. Individualized management programs can improve continence in LTC facilities but are hard to sustain. Regular monitoring and documentation of the continence status in relation to implemented continence services should be quality of care indicators for nursing homes. Pelvic floor muscle trainings with biofeedback can resolve incontinence and improve quality of life. Surgery is effective in curing stress UI in females. Clinical interventions for UI in males and for FI in adults need future investigation. A list of research recommendations is offered.

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