n -取代萘乙基咪唑啉衍生的硅二硫缩醛和锗二硫缩醛的辐射防护活性和合成。

B Célariès, G Rima, L Court, C Lion, J D Laval
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引用次数: 12

摘要

一些有机硅和有机锗的衍生物和一些相关化合物包括n -取代。制备了2-[1-萘甲基]-2-咪唑啉和2-[1-(1-萘基)乙基]-2-咪唑啉,并测定了部分化合物对小鼠的毒性。本文报道了n -取代萘咪唑衍生的硅二硫缩醛和锗二硫缩醛等新型有机硅和有机锗化合物的合成及药理活性评价。
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Radioprotective Activity and Synthesis of Siladithioacetals and Germadithioacetals Derived from N-substituted Naphthylethylimidazoline.

A number of organosilicon and organogermanium derivatives and some related compounds including the N-substituted. 2-[1-naphthylmethyl]-2-imidazoline and 2-[1-(1-naphthyl)ethyl]-2-imidazoline have been prepared and the toxicity of some compounds have been determined in mice. In this paper we report the synthesis and the evaluation of the pharmacological activity of new organosilicon and organogermanium, compounds such as sila- and germadithioacetals derived from N-substituted naphthylimidazolne.

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