骨病可以减少婴儿的阻塞性呼吸暂停:一项初步研究。

Yvan Vandenplas, Etienne Denayer, Thierry Vandenbossche, Luc Vermet, Bruno Hauser, Jean Deschepper, Agnes Engelen
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引用次数: 22

摘要

背景:阻塞性呼吸暂停是一种睡眠障碍,其特征是睡眠时呼吸暂停:呼吸因气流的物理阻塞而中断。本研究的目的是测试骨病是否会影响婴儿睡眠时阻塞性呼吸暂停的发生率。方法:招募健康婴儿34例(年龄1.5 ~ 4.0个月),随机分为两组;六个婴儿辍学了。整骨治疗组(n = 15名婴儿)在2周内接受2次整骨治疗,对照组(n = 13名婴儿)在2周内接受2次非特异性治疗。主要结果测量是在两次治疗前后8小时多导睡眠图记录期间测量的阻塞性呼吸暂停次数的变化。结果:第二次多导睡眠图记录结果显示,与对照组相比,骨病组阻塞性呼吸暂停次数明显减少(p = 0.01, Wilcoxon检验),仅显示阻塞性呼吸暂停逐渐生理性减少的趋势。但治疗后两组间阻塞性呼吸暂停下降率差异无统计学意义(p = 0.43)。结论:通过多导睡眠描记术测量,骨病可能对有阻塞性呼吸暂停病史的婴儿睡眠时阻塞性呼吸暂停的发生率有积极影响。这方面的进一步研究似乎是有必要的。
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Osteopathy may decrease obstructive apnea in infants: a pilot study.

Background: Obstructive apnea is a sleep disorder characterized by pauses in breathing during sleep: breathing is interrupted by a physical block to airflow despite effort. The purpose of this study was to test if osteopathy could influence the incidence of obstructive apnea during sleep in infants.

Methods: Thirty-four healthy infants (age: 1.5-4.0 months) were recruited and randomized in two groups; six infants dropped out. The osteopathy treatment group (n = 15 infants) received 2 osteopathic treatments in a period of 2 weeks and a control group (n = 13 infants) received 2 non-specific treatments in the same period of time. The main outcome measure was the change in the number of obstructive apneas measured during an 8-hour polysomnographic recording before and after the two treatment sessions.

Results: The results of the second polysomnographic recordings showed a significant decrease in the number of obstructive apneas in the osteopathy group (p = 0.01, Wilcoxon test), in comparison to the control group showing only a trend suggesting a gradual physiologic decrease of obstructive apneas. However, the difference in the decline of obstructive apneas between the groups after treatment was not significant (p = 0.43).

Conclusion: Osteopathy may have a positive influence on the incidence of obstructive apneas during sleep in infants with a previous history of obstructive apneas as measured by polysomnography. Additional research in this area appears warranted.

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