肝细胞癌三维灌注成像的256层多排计算机断层扫描。

Radiation medicine Pub Date : 2008-11-01 Epub Date: 2008-11-22 DOI:10.1007/s11604-008-0266-3
Tatsushi Kobayashi, Takayuki Hayashi, Shintaro Funabasama, Shinsuke Tsukagoshi, Manabu Minami, Noriyuki Moriyama
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引用次数: 10

摘要

目的:本研究的目的是通过使用256层多层螺旋CT (MDCT)扫描仪进行动态扫描来评估肝细胞癌(HCC)的三维(3D)灌注成像的临床能力。材料和方法:本研究对2例HCC患者进行了检查。他们计划接受经导管动脉输注治疗,使用动脉输注蓄水池系统。使用的CT系统是新开发的256层多层螺旋CT原型扫描仪。通过储层路径动脉内注射进行动态CT扫描,并根据三维数据进行灌注分析。结果:肿瘤组织单位体积血流量较正常肝实质明显增加。利用三维工作站,将CT图像与血流灌注图像融合显示三维血流灌注图像。结论:256层MDCT可生成三维血流灌注图像,可对hcc的血流灌注进行三维评价。
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Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography.

Purpose: The aim of this study was to evaluate the clinical capability of three-dimensional (3D) perfusion imaging of hepatocellular carcinoma (HCC) by performing dynamic scanning using a 256-slice multidetector-row CT (MDCT) scanner.

Materials and methods: Two patients with HCC were examined in this study. They were scheduled to undergo transcatheter arterial infusion therapy using an arterial infusion reservoir system. The CT system used was a newly developed prototype scanner of 256-slice MDCT. Dynamic CT scanning was performed with intraarterial injection via the reservoir route, and perfusion analysis was done based on the 3D data.

Results: The blood flow volume per unit volume in the tumors was significantly increased compared with that in normal hepatic parenchyma. Using a 3D workstation, 3D perfusion images could be displayed by fusing CT images with perfusion images about blood flow volume.

Conclusion: Three-dimensional perfusion images, which enable 3D evaluation of perfusion in HCCs, can be generated using 256-slice MDCT.

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