Takotsubo心肌病:1例报告及文献复习。

Gurpreet Singh Chahal, Sotir Polena, Babak Sanei Fard, Sreeja Natesan, Sameer Sharma, Jonas Gintautas
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摘要

Takotsubo心肌病,又称应激性心肌病和一过性左室心尖球囊综合征,是一种罕见的以射血分数一过性降低为特征的综合征。伴左心室运动不足和心尖膨大,伴有基底过度收缩和非阻塞性冠状动脉病变。Takotsubo最早于20世纪90年代初在日本被发现。它之所以这样命名,是因为它的顶部气球的形态与“takotsubo”的形状相似,takotsubo是一种底部圆、颈部窄的锅,用于捕捉章鱼。虽然Takotsubo最常见于亚洲人,但在高加索人群中的报道正变得越来越普遍,可能是由于意识和检测的提高。Takotsubo最常见的症状是急性胸痛,类似心肌梗死。患者也可能出现呼吸困难、肺水肿和更罕见的心源性休克。临床症状伴一过性左心室功能障碍。尽管临床症状与急性心肌梗死一致,但通常在心导管检查中发现正常的冠状动脉。本病例是一名亚洲妇女,在紧张的住院期间出现急性心肌梗死症状。
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Takotsubo cardiomyopathy: case report and review of the literature.

Takotsubo cardiomyopathy, also known as stress induced cardiomyopathy and transient left ventricular apical ballooning syndrome, is a rare syndrome that is characterized by a transient decrease in ejection fraction. This is accompanied by hypokinesis of the left ventricle and ballooning of the apex, with hypercontractile base and non-obstructive coronary artery disease. Takotsubo was first described in Japan in the early 1990's. It was named such due to the morphology of the apical ballooning that is similar in shape to a 'takotsubo', which is a pot with a round bottom and narrow neck used for trapping octopuses. Though most often described in Asians, reports of Takotsubo in Caucasian populations is becoming more common, possibly due to heightened awareness and detection. The most common presenting symptom of Takotsubo is acute chest pain mimicking myocardial infarction. Patients may also present with dyspnea, pulmonary edema and, more rarely, cardiogenic shock. Clinical symptoms are accompanied by transient left ventricular dysfunction. Despite clinical symptoms consistent with acute myocardial infarction, normal coronary arteries are usually detected upon cardiac catheterization. The case presented here is of an Asian woman who developed symptoms of acute myocardial infarction during a stressful hospital stay.

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