[布基纳法索瓦加杜古分离的葡萄球菌菌株对抗生素的敏感性]。

Dakar medical Pub Date : 2008-01-01
R Ouédraogo Traoré, I Sanou, D Yé-Ouattara, B Ouédraogo, Z Tarnagda
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引用次数: 0

摘要

导语:细菌的敏感性普遍下降很多,葡萄球菌对青霉素的耐药性超过80%。我们工作的目的是确定葡萄球菌的敏感性水平,特别是耐药金黄色葡萄球菌对梅西林(SARM)。材料与方法:对不同病理产物葡萄球菌分离株的敏感性进行回顾性研究。抗生素方案按照经典技术实现,在oxacilline中使用Mueller Hinton + 5% NaCl进行试验。结果:研究期间共分离到葡萄球菌1296株,其中医院金黄色葡萄球菌对青霉素G不敏感153株(10%);但对奥西林、庆大霉素和红霉素的敏感性均在80%以上。对甲氧西林敏感的金黄色葡萄球菌对庆大霉素、红霉素和环丙沙星也敏感;对甲氧西林的耐药特性对普司他霉素、万古霉素等抗生素的活性无明显影响(100%);然而,我们注意到95%以上的病例与红霉素交叉耐药。结论:虽然甲氧西林耐药菌株的存在较弱,但建议对SARM进行定期监测,并将普司他胺、环丙沙星、庆大霉素作为一线有效抗生素,万古霉素作为医院环境下的最后选择。
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[Susceptibility to antibiotics of Staphylococcus strains isolated in Ouagadougou, Burkina Faso].

Introduction: The sensibility of bacteria in a general way decreased a lot, staphylococci present a resistance to the penicillin in more than 80% of the cases. The aim of our work was to determine the level of sensibility of staphylococci, particularly that of resistant Staphylococcus aureus to Meticilline (SARM).

Material and methods: It is a retrospective study concerning the profile of sensibility of the isolated strains of staphylococci of diverse pathological products.The antibiogramme was realized according to the classic technique and for the test in the oxacilline, the Mueller Hinton + 5% of NaCl was used.

Results: during the period of study 1296 strains of staphylococcus were isolated, 153 from hospital Staphylococcus aureus were little sensitive to the penicillin G (10%); however the oxacilline, the gentamicine and the erythromycine were very active (more than 80% of sensibility.The meticillino-sensitive Staphylococcus aureus were also sensitive to the gentamycine, erythromycine and ciprofloxacine; the character of meticillino resistant did not influence the activity of antibiotics as pristinamycin and the vancomycine (100%); however we note a resistance crossed with the erythromycine in more than 95% of the cases.

Conclusion: the existence although weak of the strains meticillino resistant brings us to propose a regular surveillance of the SARM and to hold as active antibiotics of first line the pristinamycine, ciprofloxacine, gentamicine, with vancomycine as the alternative of last choice in a hospital environment.

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