新等位基因HLA-Cw*070205的全序列分析。

Tissue antigens Pub Date : 2009-11-01 Epub Date: 2009-09-08 DOI:10.1111/j.1399-0039.2009.01349.x
H-Y Zou, S-Z Jin, Z Li, L-H Cheng
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引用次数: 4

摘要

新型HLA-Cw*070205外显子1-8全长序列与HLA-Cw*07020101全长序列相同,但在第3外显子第3外显子第142个密码子上,除第3外显子第498个核苷酸由C变为T,导致第3外显子第142个密码子由ATC变为ATT的同义氨基酸替换。
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Full-length sequence of a novel allele, HLA-Cw*070205.

The full-length sequences of exons 1-8 of this novel HLA-Cw*070205 allele are identical to those of HLA-Cw*07020101, except for one nucleotide change at nt 498 in exon 3 from C to T, which result in a synonymous amino acid substitution from ATC to ATT at codon 142 in exon 3.

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来源期刊
Tissue antigens
Tissue antigens 医学-病理学
自引率
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审稿时长
6 months
期刊最新文献
Identification of a novel HLA-DRB1*14 allele, HLA-DRB1*14:143, by sequence-based typing. Identification of the novel HLA-A allele, HLA-A*24:96, in a Chinese individual. CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis. A HLA-A null allele (A*24:132N) with a stop codon in exon 3 generated by a point mutation. Detection of complement-fixing and non-fixing antibodies specific for endothelial precursor cells and lymphocytes using flow cytometry.
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