蓝藻转录的Sigma因子。

Sousuke Imamura, Munehiko Asayama
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引用次数: 112

摘要

蓝藻是一种可以进行光合作用的微生物,可以作为分析基因表达的模型。基因的表达包括转录和翻译。转录是由RNA聚合酶(RNAP)全酶完成的,包括一个核心酶和一个赋予启动子选择性的sigma (sigma)因子。本文对蓝藻sigma因子(和RNAP核心亚基)的独特结构、表达和功能进行了总结。由sigma因子识别的启动子类型也讨论了关于转录调控。
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Sigma factors for cyanobacterial transcription.

Cyanobacteria are photosynthesizing microorganisms that can be used as a model for analyzing gene expression. The expression of genes involves transcription and translation. Transcription is performed by the RNA polymerase (RNAP) holoenzyme, comprising a core enzyme and a sigma (sigma) factor which confers promoter selectivity. The unique structure, expression, and function of cyanobacterial sigma factors (and RNAP core subunits) are summarized here based on studies, reported previously. The types of promoter recognized by the sigma factors are also discussed with regard to transcriptional regulation.

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