{"title":"靶向tnf - α用于癌症治疗。","authors":"Elizabeth R Burton, Steven K Libutti","doi":"10.1186/jbiol189","DOIUrl":null,"url":null,"abstract":"<p><p>As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine TNF-alpha, and assesses its potential for gastric cancer therapy.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 9","pages":"85"},"PeriodicalIF":0.0000,"publicationDate":"2009-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol189","citationCount":"22","resultStr":"{\"title\":\"Targeting TNF-alpha for cancer therapy.\",\"authors\":\"Elizabeth R Burton, Steven K Libutti\",\"doi\":\"10.1186/jbiol189\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine TNF-alpha, and assesses its potential for gastric cancer therapy.</p>\",\"PeriodicalId\":15075,\"journal\":{\"name\":\"Journal of Biology\",\"volume\":\"8 9\",\"pages\":\"85\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/jbiol189\",\"citationCount\":\"22\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biology\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.1186/jbiol189\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biology","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1186/jbiol189","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine TNF-alpha, and assesses its potential for gastric cancer therapy.
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