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引用次数: 1
摘要
麻醉是人类历史上最有价值的发现之一。在乙醚麻醉首次公开展示后,几乎立即开始寻找更好的药物。尽管乙醚易燃性很好,但一百多年来,它一直是主要的吸入剂。1955年,一种名为氟烷的不易燃的挥发性麻醉剂问世,这一突破随之出现。该药于1958年获得FDA批准,并迅速成为美国最常用的药物。这是麻醉药物安全性的巨大飞跃。由于肝毒性,它在1988年被淘汰了。三位杰出的麻醉师:佛蒙特州的阿巴吉安、匹兹堡的锡克和杜克大学的斯蒂芬可能是美国第一个使用氟烷的人。我对这三人的文献和著作的回顾证实,杜克大学的C. Ronald Stephen博士确实是美国第一个使用并发表关于氟烷麻醉的人。