[治疗便秘的新药]。

Medizinische Klinik Pub Date : 2010-07-01 Epub Date: 2010-07-30 DOI:10.1007/s00063-010-1081-z

Birgit Adam, Tobias Liebregts, Guido Gerken

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引用次数: 1

摘要

本文综述了治疗慢性特发性便秘和肠易激综合征伴便秘的新方法。因此，本文对普卡必利和鲁比前列酮的作用机制和副作用进行了讨论。此外，目前正在评估的其他物质，如伦沙必利和利那氯肽也被描述，因为最近的研究结果显示对便秘患者有显著效果。因此，在泰加塞罗德因心脏副作用而停药后，现在有新的强效药物可用于治疗便秘。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[New drugs for the treatment of constipation].

This review introduces new therapeutic options in the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation. Therefore, prucalopride and lubiprostone are discussed including their mechanisms and side effects. In addition, other substances that are currently under evaluation such as renzapride and linaclotide are described, since recent results showed a significant effect in patients with constipation. Thus, after the withdrawal of tegaserod due to cardiac side effects, new potent drugs are now available for the treatment of constipation.

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