嘌呤2010:生物医学中的腺嘌呤核苷和核苷酸。

Idrugs Pub Date : 2010-08-01

Michal J Sereda

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引用次数: 0

摘要

在西班牙塔拉戈纳举行的“2010年嘌呤:生物医学中的腺嘌呤核苷和核苷酸”会议的主题涵盖了嘌呤能信号传导领域的新发现和嘌呤类药物的发展。本次会议报告重点介绍了嘌呤代谢信号、药物化学、嘌呤类药物的治疗潜力以及嘌呤和腺苷受体在神经退行性疾病、镰状细胞病、骨稳态、肺纤维化和疼痛中的作用。讨论的研究药物包括CF-101 (Can-Fite BioPharma Ltd/NIH/Kwang Dong Pharmaceutical Co Ltd/Seikagaku Corp)和denufosol tetrasodium(囊性纤维化基金会治疗公司/Inspire制药公司)。

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Purines 2010: Adenine Nucleosides and Nucleotides in Biomedicine.

The Purines 2010: Adenine Nucleosides and Nucleotides in Biomedicine meeting, held in Tarragona, Spain, included topics covering new findings in the field of purinergic signaling and the development of purine-based drugs. This conference report highlights selected presentations on developments in purinerigic signaling, medicinal chemistry, the therapeutic potential of purine-based drugs, and the role of purines and adenosine receptors in neurodegenerative disorders, sickle cell disease, bone homeostasis, pulmonary fibrosis and pain. Investigational drugs discussed include CF-101 (Can-Fite BioPharma Ltd/NIH/Kwang Dong Pharmaceutical Co Ltd/Seikagaku Corp) and denufosol tetrasodium (Cystic Fibrosis Foundation Therapeutics Inc/Inspire Pharmaceuticals Inc).

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