与肝血管瘤相关的红细胞增多症和血清促红细胞生成素升高

Jean-Sébastien Lanne , Jérôme Dumortier , Valérie Hervieu , Frank Pilleul , Jean-Yves Scoazec , Mustapha Adham
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引用次数: 3

摘要

背景:继发性红细胞增多症是一种罕见的疾病,通常与肿瘤或慢性肺部疾病有关。病例报告:一名41岁男性,无肝脏病史,因红细胞增多入院。临床旁调查显示血清促红细胞生成素水平升高,肝肿瘤体积大,但其鉴定不清楚。肝脏切除,组织病理学检查表明肿瘤为巨大海绵状血管瘤伴广泛黏液样改变。手术切除血管瘤后,血红蛋白和血清促红细胞生成素正常,无需进一步治疗。结论肝血管瘤必须纳入继发性红细胞增多症的罕见病因,以手术切除肝血管瘤为标准。
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Polycythemia and elevated serum erythropoietin associated with of a liver haemangioma

Background

Secondary polycythemia is a rare condition, which is usually associated to neoplasia or chronic pulmonary disorders.

Case report

A 41-year-old man man with no history of liver disease was admitted for erythrocytosis. The paraclinical investigations revealed an increased erythropoietin level in the serum and a voluminous hepatic tumor but its identification was unclear. A liver resection was performed and the histopathological examination concluded that the tumor was a giant cavernous haemangioma with extensive myxoid changes. After surgical resection of the haemangioma, normal haemoglobin and serum erythropoietin were obtained without any further treatment.

Conclusion

Liver haemangioma must be included in rare cause of secondary polycythemia, and surgical resection of the haemangioma should be considered as the standard to induce complete remission.

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