生长受体及其在伤口愈合中的作用。

Kerstin J Rolfe, Adriaan O Grobbelaar
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引用次数: 0

摘要

伤口愈合异常是当今医疗保健中的一个主要问题,瘢痕和慢性伤口影响着全世界大量的个体。伤口愈合是一个复杂的过程,涉及多种因素,包括生长因子及其受体。慢性伤口不能完成伤口愈合过程,而瘢痕形成被认为是一种过度的伤口愈合过程。生长因子受体及其配体正在被研究,以评估它们在发展治疗策略方面的潜力,以改善伤口愈合。本文综述了操纵生长因子及其相应受体治疗伤口异常愈合的潜在治疗方法。
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The growth receptors and their role in wound healing.

Abnormal wound healing is a major problem in healthcare today, with both scarring and chronic wounds affecting large numbers of individuals worldwide. Wound healing is a complex process involving several variables, including growth factors and their receptors. Chronic wounds fail to complete the wound healing process, while scarring is considered to be an overzealous wound healing process. Growth factor receptors and their ligands are being investigated to assess their potential in the development of therapeutic strategies to improve wound healing. This review discusses potential therapeutics for manipulating growth factors and their corresponding receptors for the treatment of abnormal wound healing.

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