人类生长激素异构体的诊断和治疗意义。

Marina María de Jesús Romero-Prado, Noa Beatriz Martín-Cófreces
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引用次数: 1

摘要

对人类生长激素同种异构体的研究有助于制定与非常重要的项目有关的专利:编码和调节序列,大规模生产蛋白质,修改以延长作为单体、二聚体和融合蛋白的半衰期,用于治疗与生长有关的疾病。对生长激素的鉴定和定量的设计,除了上述的设计之外,还为专利来源建立了非常重要的基础,这些专利来源可用于在涉及这些生长激素时对生物异常或不良影响进行特异性和及时的诊断和治疗。
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The diagnostic and therapeutic importance of human growth hormone isoforms.

The study of human growth hormone isoforms has conduced to the elaboration of patents related to very important items: codifying and regulatory sequences, production of the protein at large-scale, modifications to prolong half-life as monomer, dimer and fusion protein for treatments directed to growth-associated diseases. The designs to identification and quantification of hGH are besides the formers establishing very important basis of patented sources that can be used for a specific and opportune diagnosis and treatment of biological abnormalities or undesirable effects when these growth hormones are involved.

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