Marina María de Jesús Romero-Prado, Noa Beatriz Martín-Cófreces
{"title":"人类生长激素异构体的诊断和治疗意义。","authors":"Marina María de Jesús Romero-Prado, Noa Beatriz Martín-Cófreces","doi":"10.2174/187221511794839228","DOIUrl":null,"url":null,"abstract":"<p><p>The study of human growth hormone isoforms has conduced to the elaboration of patents related to very important items: codifying and regulatory sequences, production of the protein at large-scale, modifications to prolong half-life as monomer, dimer and fusion protein for treatments directed to growth-associated diseases. The designs to identification and quantification of hGH are besides the formers establishing very important basis of patented sources that can be used for a specific and opportune diagnosis and treatment of biological abnormalities or undesirable effects when these growth hormones are involved.</p>","PeriodicalId":74646,"journal":{"name":"Recent patents on DNA & gene sequences","volume":"5 1","pages":"55-67"},"PeriodicalIF":0.0000,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/187221511794839228","citationCount":"1","resultStr":"{\"title\":\"The diagnostic and therapeutic importance of human growth hormone isoforms.\",\"authors\":\"Marina María de Jesús Romero-Prado, Noa Beatriz Martín-Cófreces\",\"doi\":\"10.2174/187221511794839228\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The study of human growth hormone isoforms has conduced to the elaboration of patents related to very important items: codifying and regulatory sequences, production of the protein at large-scale, modifications to prolong half-life as monomer, dimer and fusion protein for treatments directed to growth-associated diseases. The designs to identification and quantification of hGH are besides the formers establishing very important basis of patented sources that can be used for a specific and opportune diagnosis and treatment of biological abnormalities or undesirable effects when these growth hormones are involved.</p>\",\"PeriodicalId\":74646,\"journal\":{\"name\":\"Recent patents on DNA & gene sequences\",\"volume\":\"5 1\",\"pages\":\"55-67\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2174/187221511794839228\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Recent patents on DNA & gene sequences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/187221511794839228\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Recent patents on DNA & gene sequences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/187221511794839228","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The diagnostic and therapeutic importance of human growth hormone isoforms.
The study of human growth hormone isoforms has conduced to the elaboration of patents related to very important items: codifying and regulatory sequences, production of the protein at large-scale, modifications to prolong half-life as monomer, dimer and fusion protein for treatments directed to growth-associated diseases. The designs to identification and quantification of hGH are besides the formers establishing very important basis of patented sources that can be used for a specific and opportune diagnosis and treatment of biological abnormalities or undesirable effects when these growth hormones are involved.