评估随机对照试验的偏倚风险。

Epidemiologia e psichiatria sociale Pub Date : 2010-10-01
Marianna Purgato, Corrado Barbui, Andrea Cipriani
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引用次数: 0

摘要

尽管随机对照试验是评估卫生保健干预措施有效性的首选设计,但它们也不能避免可能影响研究过程和结果有效性的偏倚。在本文中,我们讨论了如何评估试验质量,同时考虑临床试验是否以全面和完整的方式报告(与研究方案中声明的内容一致),以及试验本身的特征是否与偏倚风险相关。
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Assessing risk of bias in randomized controlled trials.

Even though randomised controlled trials are the design of choice for evaluating the efficacy of health care interventions, they are not immune to bias that may affect research process and validity of results. In the present paper we discussed how trial quality may be appraised considering both whether a clinical trial is reported in a comprehensive and complete way (consistently with what had been declared in the study protocol), and whether the characteristics of the trial itself are associated with risk of bias.

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