丝氨酸蛋白酶在体内调节肾钠转运中的潜在作用。

Nephron Physiology Pub Date : 2011-01-01 Epub Date: 2011-08-11 DOI:10.1159/000328926

G Jacquillet, I Rubera, R J Unwin

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引用次数: 7

摘要

维持钠(Na+)体内平衡是肾脏的一项基本功能。它是通过各种运输过程的本地化所有沿肾元的高度专门化段。这些转运机制受损，进而导致Na+处理，与Na+和水平衡紊乱有关，从而导致高血压和水肿。本文综述了丝氨酸蛋白酶沿整个肾元作用对钠重吸收的新调控。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Potential role of serine proteases in modulating renal sodium transport in vivo.

The maintenance of sodium (Na+) homeostasis is an essential function of the kidney. It is achieved by a variety of transport processes localized all along the highly specialised segments of the nephron. Impairment of these transport mechanisms, and thereby Na+ handling, is associated with disturbed Na+ and water balance, leading to hypertension and oedema. This review focuses on the novel regulation of sodium reabsorption by serine proteases acting along the entire nephron.

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