处方药物使用的种族差异:相关调查和行政数据的横断面分析。

Open medicine : a peer-reviewed, independent, open-access journal Pub Date : 2011-01-01 Epub Date: 2011-05-17
Steven Morgan, Gillian Hanley, Colleen Cunningham, Hude Quan
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引用次数: 0

摘要

背景:来自美国和欧洲的证据表明,处方药物的使用可能因种族而异。在加拿大,处方药物使用方面的种族差异并没有像医疗和医院护理使用方面的差异那样得到充分的记录。我们对调查和行政数据进行了横断面分析,以检查不同种族人群的处方药物使用需求调整率。方法:对居住在不列颠哥伦比亚省城市地区的19370名非土著居民,我们将2005年加拿大社区健康调查中自我认同的种族数据与描述所有已填写的处方和医疗服务使用情况的行政数据联系起来。我们使用性别分层的多变量logistic回归分析来衡量按药物类别(抗高血压药、口服抗生素、抗抑郁药、他汀类药物、呼吸系统药物和非甾体抗炎药[NSAIDs])配药可能性的差异。模型根据年龄、一般健康状况、治疗特定健康状况、社会经济因素和最近的移民(10年内)进行了调整。结果:我们发现有证据表明,处方药物的使用有显著的需求调整差异。与自认为是白人的女性和男性相比,那些南亚人或混合种族的人几乎同样有可能为大多数类型的药物配药;此外,南亚男性比白人男性更有可能服用抗生素和非甾体抗炎药。最明显的使用模式出现在中国参与者中:中国女性服用抗高血压药、抗生素、抗抑郁药和呼吸系统药物的可能性显著降低,而中国男性服用抗抑郁药和他汀类药物的可能性显著降低。解释:我们发现不同种族的研究人群在处方药使用方面存在差异。其中一些差异的性质表明,对药物的信念的种族差异可能会导致处方药使用的差异;其他差异表明在治疗使用上可能存在重要的临床差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Ethnic differences in the use of prescription drugs: a cross-sectional analysis of linked survey and administrative data.

Background: Evidence from the United States and Europe suggests that the use of prescription drugs may vary by ethnicity. In Canada, ethnic disparities in prescription drug use have not been as well documented as disparities in the use of medical and hospital care. We conducted a cross-sectional analysis of survey and administrative data to examine needs-adjusted rates of prescription drug use by people of different ethnic groups.

Methods: For 19 370 non-Aboriginal people living in urban areas of British Columbia, we linked data on self-identified ethnicity from the Canadian Community Health Survey with administrative data describing all filled prescriptions and use of medical services in 2005. We used sex-stratified multivariable logistic regression analysis to measure differences in the likelihood of filling prescriptions by drug class (antihypertensives, oral antibiotics, antidepressants, statins, respiratory drugs and nonsteroidal anti-inflammatory drugs [NSAIDs]). Models were adjusted for age, general health status, treatment-specific health status, socio-economic factors and recent immigration (within 10 years).

Results: We found evidence of significant needs-adjusted variation in prescription drug use by ethnicity. Compared with women and men who identified themselves as white, those who were South Asian or of mixed ethnicity were almost as likely to fill prescriptions for most types of medicines studied; moreover, South Asian men were more likely than white men to fill prescriptions for antibiotics and NSAIDs. The clearest pattern of use emerged among Chinese participants: Chinese women were significantly less likely to fill prescriptions for antihypertensives, antibiotics, antidepressants and respiratory drugs, and Chinese men for antidepressant drugs and statins.

Interpretation: We found some disparities in prescription drug use in the study population according to ethnic group. The nature of some of these variations suggest that ethnic differences in beliefs about pharmaceuticals may generate differences in prescription drug use; other variations suggest that there may be clinically important disparities in treatment use.

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