腹主动脉瘤破裂开放性修复术后预后的预测因素。

Chang Gung medical journal Pub Date : 2011-09-01
Hao-Jui Li, Tsung-Chi Kao, Dah-Wel Liu, Sheng-Yueh Yu, Po-Jen Ko, Hung-Chang Hsieh
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摘要

背景:确定开放性腹主动脉瘤(RAAAs)手术后早期住院死亡、30天死亡率和长期生存的相关预测因素。方法:回顾性分析1994年2月至2007年5月在台湾长庚纪念医院连续行开放手术治疗的127例RAAA患者的资料。记录的数据包括患者特征、病史、围手术期变量和结果。结果:分析中有104名男性和23名女性,平均年龄为70±12岁。raaa患者分为两组;100例(78.7%)患者归为I组(血流动力学稳定),27例(21.3%)患者归为II组(入院时血流动力学不稳定)。1组30天死亡率为22%,2组为74.1%。多因素分析确定年龄> 75岁(优势比[OR], 0.083;95%可信区间[CI] 0.02-0.36),血流动力学不稳定状态(OR, 0.081;95% CI 0.016-0.4),输血> 5l (OR, 0.14;95% CI 0.038-0.54),腹膜内破裂(OR, 7.2;95% CI 1.4-36),尿量< 0.5 mL/kg/min (OR, 22;95% CI 4.6-110)和肾上交叉夹持(OR, 0.083;95% CI 0.019-0.36)为30天死亡率的增量危险因素。结论:RAAAs患者死亡率的重要预测因素包括血流动力学不稳定、年龄> 75岁、腹膜内破裂、术中低尿量和肾上交叉夹持。
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Predictors of outcome after open repair of ruptured abdominal aortic aneurysms.

Background: To determine predictors associated with early hospital death, 30-day mortality, and long-term survival after open surgical treatment of ruptured abdominal aortic aneurysms (RAAAs).

Methods: A retrospective chart review of 127 consecutive patients who received open surgical treatment of a RAAA at Chang Gung Memorial Hospital, Taiwan, from February 1994 to May 2007. Data recorded included patient characteristics, medical history, perioperative variables, and outcomes.

Results: There were 104 men and 23 women with a mean age of 70 ∓ 12 years in the analysis. Patients with RAAAs were classified into two groups; 100 (78.7%) patients were classified as group I (hemodynamically stable), and 27 (21.3%) patients were classified as group II (hemodynamically unstable at arrival). The 30-day mortality was 22% for group I and 74.1% for group II. Multivariate analysis identified age > 75 years old (odds ratio [OR], 0.083; 95% confidence interval [CI] 0.02-0.36), hemodynamically unstable state (OR, 0.081; 95% CI 0.016-0.4), blood transfusion > 5 L (OR, 0.14; 95% CI 0.038-0.54), intraperitoneal rupture (OR, 7.2; 95% CI 1.4-36), urine output < 0.5 mL/kg/min (OR, 22; 95% CI 4.6-110), and suprarenal cross-clamping (OR, 0.083; 95% CI 0.019-0.36) as incremental risk factors for 30-day mortality.

Conclusion: Significant predictors of mortality in patients with RAAAs include hemodynamically unstable state, age > 75 years old, intraperitoneal rupture, low intraoperative urine output, and suprarenal cross-clamping.

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