[心肌炎合并多发性肌炎并发间质性肺炎1例]。

Minako Hamada, Yoshifusa Koreeda, Jiro Nakashioya, Toshifumi Kawabata, Yumiko Tomiyama, Masaharu Kawabata, Hisamichi Aizawa
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引用次数: 0

摘要

一位33岁的男性因胸片上异常阴影,干咳和用力呼吸困难而入院。入院时的胸片和高分辨率计算机断层扫描(HRCT)显示双侧背区毛玻璃影和支气管扩张伴体积损失。胸腔镜肺活检标本主要显示非特异性间质性肺炎(NSIP)。我们认为该病例为与胶原蛋白疾病相关的超敏性肺炎或间质性肺炎。口服强的松龙(PSL)起始剂量为55mg /天(1mg /kg)。然而,他主诉近端肌肉无力、疼痛和呼吸困难。由于心肌炎,他得了心力衰竭。我们通过他的症状、肌肉活检结果和血清CPK的升高,确定了IP与多肌炎相关的诊断。我们认为这个病例是由多发性肌炎引起的心肌炎。
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[A case of myocarditis associated with polymyositis preceded by interstitial pneumonia].

A 33-year old man was admitted to our hospital because of an abnormal shadow on the chest radiograph, dry cough, and exertional dyspnea. Chest radiograph and high-resolution computed tomography (HRCT) on admission showed ground-glass opacities and bronchiectasis with volume loss in the bilateral dorsal areas. Thoracoscopic lung biopsy specimens showed mainly a pattern of NSIP (nonspecific interstitial pneumonia). We considered this case as hypersensitivity pneumonia or interstitial pneumonia (IP) associated with collagen disease. Oral prednisolone (PSL) was initiated at 55 mg/day (1 mg/kg). However he complained of proximal muscle weakness and pain and difficulty of breathing. He had heart failure due to the myocarditis. We established a diagnosis of IP associated with polymyositis and it was confirmed by his symptoms, muscle biopsy findings and elevation of serum CPK. We considered this case as the myocarditis due to polymyositis.

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