第二次异体骨髓移植后t(16;21)(p11;q22)模拟自身免疫性胰腺炎的急性髓系白血病复发。

ISRN Hematology Pub Date : 2011-01-01 Epub Date: 2011-01-10 DOI:10.5402/2011/285487
Yuhei Kamada, Kazumi Suzukawa, Kenichi Taoka, Yasushi Okoshi, Yuichi Hasegawa, Shigeru Chiba
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引用次数: 8

摘要

我们报告一例37岁的女性在异基因骨髓移植治疗慢性移植物抗宿主病(cGVHD)期间急性髓性白血病(AML)复发的病例。她最初被怀疑患有自身免疫性胰腺炎。AML复发常发生在髓外部位。虽然胰腺是AML复发的罕见器官,但医生应该意识到,当排除自身免疫性胰腺炎时,胰腺肿大可能是AML复发的迹象,特别是在同种异体干细胞移植后的活动性cGVHD期间。
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Relapse of Acute Myeloid Leukemia with t(16;21)(p11;q22) Mimicking Autoimmune Pancreatitis after Second Allogeneic Bone Marrow Transplantation.

We report the case of a 37-year-old woman who had a relapse of acute myeloid leukemia (AML) during treatment for chronic graft versus host disease (cGVHD) after allogeneic bone marrow transplantation. She was originally suspected of having autoimmune pancreatitis. Relapse of AML often occurs at extramedullary sites. Whereas the pancreas is rare as an organ of AML relapse, physicians should be aware that enlargement of the pancreas could be a sign of relapsed AML when excluding autoimmune pancreatitis, particularly during active cGVHD after allogeneic stem cell transplantation.

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