Frank J Penedo, Lara Traeger, Catherine Benedict, Giovana Thomas, Jason R Dahn, Madeline Hernandez Krause, W Jarrard Goodwin
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Psychosocial factors such as social support may explain individual variance in DSQOL outcomes.</p><p><strong>Objective: </strong>The researchers sought to evaluate changes in perceived availability of social support from pretreatment to posttreatment and to determine whether decreases in perceived social support predicted poorer posttreatment DSQOL among HNC patients, controlling for disease- and treatment-related factors.</p><p><strong>Methods: </strong>Participants (n = 32) were newly diagnosed with HNC and were awaiting surgery and/or radiation treatment. Measures included the ENRICHD Social Support instrument (ESSI) to assess perceived social support and the Functional Assessment of Cancer Therapy-Head & Neck (FACT-H&N) to assess DSQOL. Paired-samples t-tests and hierarchical regression analyses were conducted to determine relationships between pretreatment and posttreatment perceived social support and DSQOL.</p><p><strong>Results: </strong>Perceived social support decreased significantly from pre- to posttreatment (F[31] = -2.71, P < .01). After adjusting for relevant covariates and pretreatment DSQOL, change in perceived social support remained a significant predictor of posttreatment DSQOL (β = .47, P < .01).</p><p><strong>Limitations: </strong>This study included a relatively small sample of HNC patients, which limited power to evaluate mechanisms of observed relationships.</p><p><strong>Conclusions: </strong>Increased social isolation may be a risk factor for poorer physical recovery from, or adjustment to, treatment-related side effects. Social support may be an important target for psychosocial interventions for patients who face challenging treatment side effects.</p>","PeriodicalId":75116,"journal":{"name":"The journal of supportive oncology","volume":"10 3","pages":"119-23"},"PeriodicalIF":0.0000,"publicationDate":"2012-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.suponc.2011.09.002","citationCount":"34","resultStr":"{\"title\":\"Perceived social support as a predictor of disease-specific quality of life in head-and-neck cancer patients.\",\"authors\":\"Frank J Penedo, Lara Traeger, Catherine Benedict, Giovana Thomas, Jason R Dahn, Madeline Hernandez Krause, W Jarrard Goodwin\",\"doi\":\"10.1016/j.suponc.2011.09.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Treatment for head-and-neck cancer (HNC) can lead to severe decrements in disease-specific quality of life (DSQOL) due to disfigurement and disability in speech, eating, and/or breathing. Psychosocial factors such as social support may explain individual variance in DSQOL outcomes.</p><p><strong>Objective: </strong>The researchers sought to evaluate changes in perceived availability of social support from pretreatment to posttreatment and to determine whether decreases in perceived social support predicted poorer posttreatment DSQOL among HNC patients, controlling for disease- and treatment-related factors.</p><p><strong>Methods: </strong>Participants (n = 32) were newly diagnosed with HNC and were awaiting surgery and/or radiation treatment. Measures included the ENRICHD Social Support instrument (ESSI) to assess perceived social support and the Functional Assessment of Cancer Therapy-Head & Neck (FACT-H&N) to assess DSQOL. Paired-samples t-tests and hierarchical regression analyses were conducted to determine relationships between pretreatment and posttreatment perceived social support and DSQOL.</p><p><strong>Results: </strong>Perceived social support decreased significantly from pre- to posttreatment (F[31] = -2.71, P < .01). After adjusting for relevant covariates and pretreatment DSQOL, change in perceived social support remained a significant predictor of posttreatment DSQOL (β = .47, P < .01).</p><p><strong>Limitations: </strong>This study included a relatively small sample of HNC patients, which limited power to evaluate mechanisms of observed relationships.</p><p><strong>Conclusions: </strong>Increased social isolation may be a risk factor for poorer physical recovery from, or adjustment to, treatment-related side effects. 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引用次数: 34
摘要
背景:头颈癌(HNC)的治疗可导致疾病特异性生活质量(DSQOL)的严重下降,原因是言语、饮食和/或呼吸方面的毁容和残疾。社会支持等社会心理因素可以解释DSQOL结果的个体差异。目的:研究人员试图评估从治疗前到治疗后感知到的社会支持可用性的变化,并确定感知到的社会支持的减少是否预示着HNC患者治疗后较差的DSQOL,控制疾病和治疗相关因素。方法:参与者(n = 32)新诊断为HNC,正在等待手术和/或放射治疗。测量方法包括用enrichment社会支持工具(ESSI)评估感知社会支持,用FACT-H&N评估癌症治疗-头颈部功能评估(FACT-H&N)评估DSQOL。采用配对样本t检验和分层回归分析确定治疗前后感知社会支持与DSQOL之间的关系。结果:治疗前后感知社会支持显著下降(F[31] = -2.71, P < 0.01)。在调整相关协变量和预处理DSQOL后,感知社会支持的变化仍然是治疗后DSQOL的显著预测因子(β = 0.47, P < 0.01)。局限性:本研究纳入了相对较小的HNC患者样本,这限制了评估观察到的关系机制的能力。结论:增加的社会隔离可能是治疗相关副作用后较差的身体恢复或适应的危险因素。对于面临治疗副作用的患者,社会支持可能是社会心理干预的重要目标。
Perceived social support as a predictor of disease-specific quality of life in head-and-neck cancer patients.
Background: Treatment for head-and-neck cancer (HNC) can lead to severe decrements in disease-specific quality of life (DSQOL) due to disfigurement and disability in speech, eating, and/or breathing. Psychosocial factors such as social support may explain individual variance in DSQOL outcomes.
Objective: The researchers sought to evaluate changes in perceived availability of social support from pretreatment to posttreatment and to determine whether decreases in perceived social support predicted poorer posttreatment DSQOL among HNC patients, controlling for disease- and treatment-related factors.
Methods: Participants (n = 32) were newly diagnosed with HNC and were awaiting surgery and/or radiation treatment. Measures included the ENRICHD Social Support instrument (ESSI) to assess perceived social support and the Functional Assessment of Cancer Therapy-Head & Neck (FACT-H&N) to assess DSQOL. Paired-samples t-tests and hierarchical regression analyses were conducted to determine relationships between pretreatment and posttreatment perceived social support and DSQOL.
Results: Perceived social support decreased significantly from pre- to posttreatment (F[31] = -2.71, P < .01). After adjusting for relevant covariates and pretreatment DSQOL, change in perceived social support remained a significant predictor of posttreatment DSQOL (β = .47, P < .01).
Limitations: This study included a relatively small sample of HNC patients, which limited power to evaluate mechanisms of observed relationships.
Conclusions: Increased social isolation may be a risk factor for poorer physical recovery from, or adjustment to, treatment-related side effects. Social support may be an important target for psychosocial interventions for patients who face challenging treatment side effects.