连续肋间神经阻滞治疗肋骨骨折:准备好了吗?

Michael S Truitt, Jason Murry, Joseph Amos, Manuel Lorenzo, Alicia Mangram, Ernest Dunn, Ernest E Moore
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引用次数: 107

摘要

背景:为肋骨骨折患者提供镇痛仍然是一个管理挑战。本研究的目的是检查我们使用连续肋间神经阻滞(CINB)的经验。虽然这项技术正在使用,但很少有数据发表,记录其使用和疗效。我们假设CINB可以提供良好的镇痛效果,改善肺功能,缩短住院时间(LOS)。方法:对连续3例或3例以上单侧肋骨骨折的成人钝性创伤患者进行24个月的前瞻性研究。导管放置于床边胸外、椎旁位置,输注0.2%罗哌卡因。静息和咳嗽后分别测定呼吸频率、预置(PRE)数值疼痛量表(NPS)评分和持续最大吸气(SMI)肺容量。置管后60分钟重复参数。医院使用硬膜外镇痛与历史对照进行LOS比较。结果:在研究期间,102例患者符合纳入标准。平均年龄69岁(21 ~ 96岁),平均损伤严重程度评分14分(9 ~ 16分),平均肋骨骨折5.8例(3 ~ 10例)。平均NPS显著改善(休息时PRE NPS = 7.5 vs.休息时POST NPS = 2.6, p < 0.05,咳嗽后PRE NPS = 9.4,咳嗽后POST = 3.6, p < 0.05),且与SMI升高相关(PRE SMI = 0.4 L, POST SMI = 1.3 L, p < 0.05)。呼吸频率显著降低(p < 0.05), 102例患者中仅有2例需要机械通气。研究人群的平均生存期为2.9天,而历史对照组为5.9天。无手术或药物相关并发症发生。结论:使用CINB可显著改善肋骨骨折患者的肺功能、疼痛控制并缩短LOS。
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Continuous intercostal nerve blockade for rib fractures: ready for primetime?

Background: Providing analgesia for patients with rib fractures continues to be a management challenge. The objective of this study was to examine our experience with the use of a continuous intercostal nerve block (CINB). Although this technique is being used, little data have been published documenting its use and efficacy. We hypothesized that a CINB would provide excellent analgesia, improve pulmonary function, and decrease length of stay (LOS).

Methods: Consecutive adult blunt trauma patients with three or more unilateral rib fractures were prospectively studied over 24 months. The catheters were placed at the bedside in the extrathoracic, paravertebral location, and 0.2% ropivacaine was infused. Respiratory rate, preplacement (PRE) numeric pain scale (NPS) scores, and sustained maximal inspiration (SMI) lung volumes were determined at rest and after coughing. Parameters were repeated 60 minutes after catheter placement (POST). Hospital LOS comparison was made with historical controls using epidural analgesia.

Results: Over the study period, 102 patients met inclusion criteria. Mean age was 69 (21-96) years, mean injury severity score was 14 (9-16), and the mean number of rib fractures was 5.8 (3-10). Mean NPS improved significantly (PRE NPS at rest = 7.5 vs. POST NPS at rest = 2.6, p < 0.05, PRE NPS after cough = 9.4, POST after cough = 3.6, p < 0.05) which was associated with an increase in the SMI (PRE SMI = 0.4 L and POST SMI = 1.3 L, p < 0.05). Respiratory rate decreased significantly (p < 0.05) and only 2 of 102 required mechanical ventilation. Average LOS for the study population was 2.9 days compared with 5.9 days in the historical control. No procedural or drug-related complications occurred.

Conclusion: Utilization of CINB significantly improved pulmonary function, pain control, and shortens LOS in patients with rib fractures.

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来源期刊
Journal of Trauma-Injury Infection and Critical Care
Journal of Trauma-Injury Infection and Critical Care CRITICAL CARE MEDICINE-EMERGENCY MEDICINE
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