[塞内加尔6例右侧感染性心内膜炎的流行病学、临床及超声检查]。

M B Ndiaye, M Diao, S Pessinaba, M Bodian, A D Kane, Ad Mbaye, M M Dia, E C C Ciss, M Sarr, A Kane, S A Ba
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引用次数: 0

摘要

右侧感染性心内膜炎占心内膜受累的5%至10%,通常影响三尖瓣。本报告的目的是描述2007年12月至2010年2月在塞内加尔达喀尔Aristide Le Dantec医院心内科观察到的6例右侧感染性心内膜炎的流行病学、临床和超声心动图方面的情况。诊断依据杜克大学修订后的标准。男性3名,女性3名,平均年龄28.2岁(范围:20岁和43岁)。6例患者中有5例出现三尖瓣心内膜炎,其中1例合并肺心内膜炎。另一例肺心内膜炎合并主动脉心内膜炎。感染性心内膜炎3例为急性,4例为原发性。法洛四联症并发感染性心内膜炎1例。发热4例,平均体温38.4℃(范围37.2 ~ 40℃),心力衰竭5例。2例患者血培养金黄色葡萄球菌阳性。所有患者均有嗜中性粒细胞为主的白细胞增多症。多普勒超声心动图显示所有病例均有植被。1例为先天性心脏病,2例为静脉置管,2例为口腔感染。无患者静脉吸毒成瘾或感染艾滋病毒。结果包括一例难治性心力衰竭的院内死亡。右侧心内膜炎通常是原发的,以三尖瓣受累为主。它影响两性。影响因素包括产后静脉置管和牙齿感染。预防需要在静脉导管插入期间严格的无菌,治疗牙齿感染和改善先天性心脏病的管理。
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[Epidemiological, clinical and ultrasonographic aspects of right-sided infective endocarditis in Senegal: 6 cases].

Right-sided infective endocarditis accounts for 5 to 10% of endocarditic involvement and usually affects the tricuspid valve. The purpose of this report is to describe epidemiological, clinical and echocardiographical aspects of 6 cases of right-sided infective endocarditis observed in the Cardiology Department of Aristide Le Dantec Hospital in Dakar, Senegal from December 2007 to February 2010. Diagnosis was based on Duke's modified criteria. There were 3 men and 3 women with a mean age of 28.2 years (range: 20 and 43). Five of the 6 patients presented tricuspid endocarditis including one case associated with pulmonary endocarditis. In another case, pulmonary endocarditis was associated with aortic endocarditis. Infective endocarditis was acute in three cases and primary in four. One case of infective endocarditis was observed in a tetralogy of Fallot. Fever was present in 4 cases with an mean temperature of 38.4 degrees C (range, 37.2 to 40 degrees C) and heart failure was present in 5 cases. In 2 patients, blood cultures were positive for Staphylococcus aureus. All patients had leucocytosis with a neutrophilic predominance. Doppler echocardiography depicted vegetations in all cases. Contributing factors included congenital heart disease in 1 case, insertion of a venous catheter in 2 and dental infection in 2. No patient was addicted to intravenous drugs or infected by HIV. Outcomes included one in-hospital death with signs of refractory heart failure. Right-sided endocarditis is often primary and is dominated by the tricuspid involvement. It affects both sexes. Contributing factors include venous catheterization during the postpartum period and dental infection. Prevention requires strict asepsis during venous catheter insertion, treatment of dental infections and improved management of congenital heart disease.

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