发源于大网膜的炎性肌成纤维细胞瘤1例。

Journal of the Korean Surgical Society Pub Date : 2012-06-01 Epub Date: 2012-05-29 DOI:10.4174/jkss.2012.82.6.380
Bong Hyeon Kye, Hyung Jin Kim, Se-Goo Kang, Changyoung Yoo, Hyeon-Min Cho
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引用次数: 12

摘要

炎症性肌纤维母细胞瘤是一种罕见的实体瘤,常发生在儿童身上。IMF肿瘤主要发生在肺,但肿瘤可影响任何有变异性表现的器官系统。一位22岁的女性被评估为可触及的下腹部肿块,其大小自两个月前一直在增加。腹部计算机断层扫描显示回肠肠系膜一分叶状、非均匀增强的软组织肿块,大小为6.5 × 5.7 cm。在手术中,肿块起源于位于盆腔的大网膜,并被完全切除,没有肿瘤溢出。组织学上,肿块为梭形细胞病变,有严重的异型性和有丝分裂。免疫组化示间变性淋巴瘤激酶-1为IMF肿瘤。由于其局部侵袭性和复发倾向,该肿瘤可与软组织肉瘤混淆。提高医生对这种实体的认识应该有助于认识其临床特征和实验室结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A case of inflammatory myofibroblastic tumor originated from the greater omentum in young adult.

Inflammatory myofibroblastic (IMF) tumor is a rare solid tumor that often affects children. IMF tumors occur primarily in the lung, but the tumor may affect any organ system with protean manifestations. A 22-year-old woman was evaluated for palpable low abdominal mass that had been increasing in size since two months prior. Abdominal computed tomography showed a lobulated, heterogeneous contrast enhancing soft tissue mass, 6.5 × 5.7 cm in size in the ileal mesentery. At surgery, the mass originated from the greater omentum laying in the pelvic cavity and was completely excised without tumor spillage. Histologically, the mass was a spindle cell lesion with severe atypism and some mitosis. Immunohistochemistry for anaplastic lymphoma kinase-1 revealed that the lesion was an IMF tumor. Because of its local invasiveness and its tendency to recur, this tumor can be confused with a soft tissue sarcoma. Increasing physician awareness of this entity should facilitate recognition of its clinical characteristics and laboratory findings.

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