OPTIMISE研究(优化2型糖尿病管理,包括基准和标准治疗)。卢森堡的结果]。

G Michel
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摘要

OPTIMISE研究(NCT00681850)已在包括卢森堡在内的6个欧洲国家开展,以主要可改变的血管危险因素作为关键质量指标,前瞻性评估基准对2型糖尿病患者初级保健质量的影响。治疗2型糖尿病患者的初级保健中心被随机分为标准治疗组(对照组)或标准治疗组(参照每个国家其他中心的反馈)。主要终点是基准组患者在12个月随访后达到预先设定的关键质量指标目标的百分比:糖化血红蛋白(HbAlc),收缩压(SBP)和低密度脂蛋白(LDL)胆固醇。在卢森堡,在基准组中,更多的患者达到了收缩压(40.2%对20%)和低密度脂蛋白胆固醇(50.4%对44.2%)的目标。与对照组(8.3%)相比,基准组中12.9%的患者达到了所有三个目标。在这项随机对照研究中,基准测试被证明是改善关键质量指标目标的有效工具,这些指标是2型糖尿病主要可改变的血管危险因素。
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[The OPTIMISE study (Optimal Type 2 Diabetes Management Including Benchmarking and Standard Treatment]. Results for Luxembourg].

The OPTIMISE study (NCT00681850) has been run in six European countries, including Luxembourg, to prospectively assess the effect of benchmarking on the quality of primary care in patients with type 2 diabetes, using major modifiable vascular risk factors as critical quality indicators. Primary care centers treating type 2 diabetic patients were randomized to give standard care (control group) or standard care with feedback benchmarked against other centers in each country (benchmarking group). Primary endpoint was percentage of patients in the benchmarking group achieving pre-set targets of the critical quality indicators: glycated hemoglobin (HbAlc), systolic blood pressure (SBP) and low-density lipoprotein (LDL) cholesterol after 12 months follow-up. In Luxembourg, in the benchmarking group, more patients achieved target for SBP (40.2% vs. 20%) and for LDL-cholesterol (50.4% vs. 44.2%). 12.9% of patients in the benchmarking group met all three targets compared with patients in the control group (8.3%). In this randomized, controlled study, benchmarking was shown to be an effective tool for improving critical quality indicator targets, which are the principal modifiable vascular risk factors in diabetes type 2.

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