Shih-Yin Chen PhD , Julie Vanderpoel PharmD, MPA , Samir Mody PharmD, MBA , Winnie W. Nelson PharmD, MS , Jeffrey Schein DrPH, MPH , Preethi Rao BA , Luke Boulanger MA, MBA
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A logistic regression<span> model was used to assess factors associated with receiving anticoagulants<span> in a subgroup of patients with AF whose treatment pattern was established for 2 consecutive years. Sample weights were applied to obtain nationally representative estimates.</span></span></p></div><div><h3>Results</h3><p>A total of 2990 patients with AF and 5980 control patients were included in the burden of disease analysis, and 1481 patients with AF were included in the anticoagulant predictor analysis. Patients with AF had a higher level of comorbidity (Charlson Comorbidity Index: 3.3 vs 1.5; <em>P</em> < 0.05), worse self-perceived health status (<em>P</em> < 0.001), and greater level of disability (<em>P</em> < 0.001) than their matched counterparts. A greater proportion of patients with AF required caregiver assistance (62.8% vs 51.5%; <em>P</em><span> < 0.001). Logistic regression found that higher Charlson Comorbidity Index<span> scores, difficulty in obtaining necessary health care, older age, being widowed, a history of psychiatric disorders, and being underweight decreased the likelihood of receiving anticoagulant therapy.</span></span></p></div><div><h3>Conclusions</h3><p><span>In a Medicare population, a greater need for caregiver assistance was observed in patients with AF. Subgroups characterized by </span>frailty or inability for self-care were identified as being less likely to receive anticoagulant therapy. The need for caregiver assistance among patients with AF, as well as the patient subgroups identified as less likely to receive anticoagulant therapy, should be considered when making treatment decisions.</p></div>","PeriodicalId":50811,"journal":{"name":"American Journal Geriatric Pharmacotherapy","volume":"10 5","pages":"Pages 273-283"},"PeriodicalIF":0.0000,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.amjopharm.2012.08.003","citationCount":"5","resultStr":"{\"title\":\"Caregiver Assistance Among Medicare Beneficiaries With Atrial Fibrillation and Factors Associated With Anticoagulant Treatment\",\"authors\":\"Shih-Yin Chen PhD , Julie Vanderpoel PharmD, MPA , Samir Mody PharmD, MBA , Winnie W. Nelson PharmD, MS , Jeffrey Schein DrPH, MPH , Preethi Rao BA , Luke Boulanger MA, MBA\",\"doi\":\"10.1016/j.amjopharm.2012.08.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Atrial fibrillation<span> (AF) is the most common sustained cardiac arrhythmia and disproportionately affects the elderly.</span></p></div><div><h3>Objective</h3><p>This study describes patient characteristics<span> and caregiver assistance among Medicare beneficiaries with AF and examines factors associated with receiving anticoagulant treatment.</span></p></div><div><h3>Methods</h3><p>Patients with AF and age/gender-matched controls were identified from Medicare Current Beneficiary Survey data from 2001 to 2006. A logistic regression<span> model was used to assess factors associated with receiving anticoagulants<span> in a subgroup of patients with AF whose treatment pattern was established for 2 consecutive years. Sample weights were applied to obtain nationally representative estimates.</span></span></p></div><div><h3>Results</h3><p>A total of 2990 patients with AF and 5980 control patients were included in the burden of disease analysis, and 1481 patients with AF were included in the anticoagulant predictor analysis. Patients with AF had a higher level of comorbidity (Charlson Comorbidity Index: 3.3 vs 1.5; <em>P</em> < 0.05), worse self-perceived health status (<em>P</em> < 0.001), and greater level of disability (<em>P</em> < 0.001) than their matched counterparts. A greater proportion of patients with AF required caregiver assistance (62.8% vs 51.5%; <em>P</em><span> < 0.001). Logistic regression found that higher Charlson Comorbidity Index<span> scores, difficulty in obtaining necessary health care, older age, being widowed, a history of psychiatric disorders, and being underweight decreased the likelihood of receiving anticoagulant therapy.</span></span></p></div><div><h3>Conclusions</h3><p><span>In a Medicare population, a greater need for caregiver assistance was observed in patients with AF. Subgroups characterized by </span>frailty or inability for self-care were identified as being less likely to receive anticoagulant therapy. The need for caregiver assistance among patients with AF, as well as the patient subgroups identified as less likely to receive anticoagulant therapy, should be considered when making treatment decisions.</p></div>\",\"PeriodicalId\":50811,\"journal\":{\"name\":\"American Journal Geriatric Pharmacotherapy\",\"volume\":\"10 5\",\"pages\":\"Pages 273-283\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.amjopharm.2012.08.003\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal Geriatric Pharmacotherapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1543594612001109\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal Geriatric Pharmacotherapy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1543594612001109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
房颤(AF)是最常见的持续性心律失常,对老年人的影响尤为严重。目的:本研究描述了AF医疗保险受益人的患者特征和护理人员的帮助,并探讨了接受抗凝治疗的相关因素。方法从2001年至2006年的医疗保险受益人调查数据中确定房颤患者和年龄/性别匹配的对照组。采用logistic回归模型评估连续2年治疗模式确定的房颤亚组患者接受抗凝治疗的相关因素。使用样本权重来获得具有全国代表性的估计。结果共有2990例房颤患者和5980例对照患者被纳入疾病负担分析,1481例房颤患者被纳入抗凝预测分析。房颤患者的合并症水平更高(Charlson共病指数:3.3 vs 1.5;P & lt;0.05),自我感觉健康状况较差(P <0.001)和更大程度的残疾(P <0.001)。房颤患者需要护理人员帮助的比例更高(62.8% vs 51.5%;P & lt;0.001)。逻辑回归发现,较高的Charlson合并症指数评分、难以获得必要的医疗保健、年龄较大、丧偶、有精神疾病史和体重过轻降低了接受抗凝治疗的可能性。结论:在医疗保险人群中,观察到AF患者对护理人员帮助的需求更大。以虚弱或无法自我护理为特征的亚组被认为不太可能接受抗凝治疗。在做出治疗决定时,应考虑房颤患者以及不太可能接受抗凝治疗的患者亚组对护理人员帮助的需求。
Caregiver Assistance Among Medicare Beneficiaries With Atrial Fibrillation and Factors Associated With Anticoagulant Treatment
Background
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and disproportionately affects the elderly.
Objective
This study describes patient characteristics and caregiver assistance among Medicare beneficiaries with AF and examines factors associated with receiving anticoagulant treatment.
Methods
Patients with AF and age/gender-matched controls were identified from Medicare Current Beneficiary Survey data from 2001 to 2006. A logistic regression model was used to assess factors associated with receiving anticoagulants in a subgroup of patients with AF whose treatment pattern was established for 2 consecutive years. Sample weights were applied to obtain nationally representative estimates.
Results
A total of 2990 patients with AF and 5980 control patients were included in the burden of disease analysis, and 1481 patients with AF were included in the anticoagulant predictor analysis. Patients with AF had a higher level of comorbidity (Charlson Comorbidity Index: 3.3 vs 1.5; P < 0.05), worse self-perceived health status (P < 0.001), and greater level of disability (P < 0.001) than their matched counterparts. A greater proportion of patients with AF required caregiver assistance (62.8% vs 51.5%; P < 0.001). Logistic regression found that higher Charlson Comorbidity Index scores, difficulty in obtaining necessary health care, older age, being widowed, a history of psychiatric disorders, and being underweight decreased the likelihood of receiving anticoagulant therapy.
Conclusions
In a Medicare population, a greater need for caregiver assistance was observed in patients with AF. Subgroups characterized by frailty or inability for self-care were identified as being less likely to receive anticoagulant therapy. The need for caregiver assistance among patients with AF, as well as the patient subgroups identified as less likely to receive anticoagulant therapy, should be considered when making treatment decisions.