用于衡量资源有限医院风险调整后手术效果的简明工具。

Jamie E Anderson, Randi Lassiter, Stephen W Bickler, Mark A Talamini, David C Chang
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引用次数: 0

摘要

目标开发并验证一种风险调整工具,用少于 10 个变量来衡量资源有限医院的手术效果:设计:使用国家外科质量改进计划(NSQIP)的所有术前变量来建立预测住院患者死亡率的模型。这些模型是根据接受者运算特征曲线下面积(AUROC)依次添加变量建立的,并使用数据集之外的一家医院的病历审查数据进行外部验证。设置 模型开发基于 2005 年至 2009 年的 NSQIP 数据。验证基于美国 1 家非城市医院 2009 年至 2010 年的数据:主要结果指标:每个模型的AUROC值:只有3个变量(美国麻醉医师协会等级、手术时的功能状态和年龄)的AUROC值达到90%以上。使用 4 个变量后,AUROC 值增至 91%,但使用其他变量后,AUROC 值没有显著增加。在验证时,AUROC最高的模型是相同的3变量模型(0.9398):结论:开发预测住院病人死亡率的风险调整工具所需的变量可能少于 6 个,从而将收集变量的成本降低 95%。在资源匮乏的环境中,包括低收入和中等收入国家,这些变量应该很容易收集,从而在全球范围内创建首个衡量手术结果的标准化工具。目前还需要进行研究,以确定这些有限变量模型中哪一个最适合各种临床环境。
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Brief tool to measure risk-adjusted surgical outcomes in resource-limited hospitals.

Objectives: To develop and validate a risk-adjusted tool with fewer than 10 variables to measure surgical outcomes in resource-limited hospitals.

Design: All National Surgical Quality Improvement Program (NSQIP) preoperative variables were used to develop models to predict inpatient mortality. The models were built by sequential addition of variables selected based on their area under the receiver operator characteristic curve (AUROC) and externally validated using data based on medical record reviews at 1 hospital outside the data set. SETTING Model development was based on data from the NSQIP from 2005 to 2009. Validation was based on data from 1 nonurban hospital in the United States from 2009 to 2010.

Patients: A total of 631 449 patients in NSQIP and 239 patients from the validation hospital.

Main outcome measures: The AUROC value for each model.

Results: The AUROC values reached higher than 90% after only 3 variables (American Society of Anesthesiologists class, functional status at time of surgery, and age). The AUROC values increased to 91% with 4 variables but did not increase significantly with additional variables. On validation, the model with the highest AUROC was the same 3-variable model (0.9398).

Conclusions: Fewer than 6 variables may be necessary to develop a risk-adjusted tool to predict inpatient mortality, reducing the cost of collecting variables by 95%. These variables should be easily collectable in resource-poor settings, including low- and middle-income countries, thus creating the first standardized tool to measure surgical outcomes globally. Research is needed to determine which of these limited-variable models is most appropriate in a variety of clinical settings.

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Archives of Surgery
Archives of Surgery 医学-外科
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