冠状动脉手术后15年生存率相似,与左主干狭窄无关。

Torbjörn Ivert, Bengt Brorsson
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引用次数: 0

摘要

目的:评价冠状动脉旁路移植术(CABG)后15年生存率与左主干狭窄(LMS)和右冠状动脉阻塞(RCA)的关系。设计:前瞻性收集1994-1995年期间因稳定性心绞痛行冠脉搭桥的977例患者的冠状动脉造影结果,并纳入瑞典冠状动脉血运重建术-瑞典技术委员会评估研究。结果:五分之一的患者存在明显的LMS, 61%的LMS患者和68%的非LMS患者发现明显的RCA阻塞。患者分为无LMS组(I组)、LMS不伴RCA阻塞组(II组)和LMS伴右冠状动脉(RCA)明显阻塞组(III组)。三组患者的早期死亡率无差异,I、II、III组患者的早期死亡率分别为1.2%、1.2%和0.8%。相应的15年生存率分别为51%、47%和47%。在多变量分析中,年龄较大、吸烟、严重心绞痛、应激试验阳性、高血压、糖尿病和射血分数< 50%是15岁死亡的危险因素。结论:冠脉搭桥后15年的死亡与临床变量相关,但与LMS存在或不存在显著相关的RCA阻塞无关。
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Similar survival 15 years after coronary artery surgery irrespective of left main stem stenosis.

Objectives: To evaluate 15-year survival after coronary artery bypass grafting (CABG) in relation to grade left main stenosis (LMS) and right coronary artery (RCA) obstruction.

Design: Coronary angiographic findings were prospectively collected in 977 patients who had CABG for stable angina during 1994-1995 and were included in the Swedish Coronary Revascularization - Swedish Council of Technology Assessment study.

Results: Significant LMS was present in one fifth of the patients and significant RCA obstruction was found in 61% of those with LMS and in 68% of patients without LMS. The patients were categorized as no LMS (Group I), LMS without RCA obstruction (Group II) or significant LMS with significant right coronary artery (RCA) obstruction (Group III). Early mortality did not differ in the three groups and was 1.2, 1.2% and 0.8% in group I, II and III, respectively. Corresponding survival at 15 years was similar 51%, 47% and 47%, respectively. In multivariable analysis older age, smoking, severe angina, positive stress test, hypertension, diabetes mellitus and ejection fraction < 50% were risk factors for death at 15 years.

Conclusions: Death 15 years after CABG correlated to clinical variables but was not predicted from presence of LMS with or without significant associated RCA obstruction.

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Abstracts of the XV Swedish Cardiovascular Spring Meeting. Göteborg, Sweden. April 17–19, 2013. Aortic regurgitation after transcatheter aortic valve implantation of the Edwards SAPIEN ™ valve. Preoperative NT-proBNP independently predicts outcome in patients with acute coronary syndrome undergoing CABG. Sildenafil after cardiac arrest and infarction; an experimental rat model. Similar survival 15 years after coronary artery surgery irrespective of left main stem stenosis.
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