用于DBS定位的三维可变形脑图谱。1 .图集创建和人工制品减少的方法。

Q4 Medicine Open Neuroimaging Journal Pub Date : 2012-01-01 Epub Date: 2012-10-05 DOI:10.2174/1874440001206010092

Atchar Sudhyadhom, Michael S Okun, Kelly D Foote, Maryam Rahman, Frank J Bova

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引用次数: 26

摘要

背景:脑深部刺激(DBS)的靶向治疗在很大程度上依赖于精确定位特定解剖脑结构的能力。皮质下结构的直接靶向一直受到相关DBS靶点可视化能力的限制。方法和结果:在这项工作中，我们描述了一种用于为DBS手术创建三维可变形图谱的方法的开发和实施。这个地图集被设计成与沙尔滕布兰德-贝利地图集结构轮廓的印刷版本相对应。我们采用平滑技术来减少印刷品中固有的伪影。结论:我们提出了用于创建三维患者特异性DBS图谱的方法，该图谱可能在未来用于临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Three-dimensional Deformable Brain Atlas for DBS Targeting. I. Methodology for Atlas Creation and Artifact Reduction.

Background: Targeting in deep brain stimulation (DBS) relies heavily on the ability to accurately localize particular anatomic brain structures. Direct targeting of subcortical structures has been limited by the ability to visualize relevant DBS targets.

Methods and results: In this work, we describe the development and implementation, of a methodology utilized to create a three dimensional deformable atlas for DBS surgery. This atlas was designed to correspond to the print version of the Schaltenbrand-Bailey atlas structural contours. We employed a smoothing technique to reduce artifacts inherent in the print version.

Conclusions: We present the methodology used to create a three dimensional patient specific DBS atlas which may in the future be tested for clinical utility.

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来源期刊

Open Neuroimaging Journal Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

0.70

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0.00%

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期刊介绍： The Open Neuroimaging Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, and letters in all important areas of brain function, structure and organization including neuroimaging, neuroradiology, analysis methods, functional MRI acquisition and physics, brain mapping, macroscopic level of brain organization, computational modeling and analysis, structure-function and brain-behavior relationships, anatomy and physiology, psychiatric diseases and disorders of the nervous system, use of imaging to the understanding of brain pathology and brain abnormalities, cognition and aging, social neuroscience, sensorimotor processing, communication and learning.