造口旁疝的发生率及危险因素。

Yeun Ju Sohn, Sun Mi Moon, Ui Sup Shin, Sun Hee Jee
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引用次数: 60

摘要

目的:在各种造口并发症中,造口旁疝(PSH)最为常见。预防PSH对提高生活质量和防止进一步的严重并发症非常重要。本研究的目的是分析PSH的发病率和危险因素。方法:从2002年1月至2008年10月,我们回顾性分析了165例接受末端结肠造口术的患者。作为常规的肿瘤随访,腹部-骨盆计算机断层扫描用于检查PSH的发生。分析年龄、性别、体重指数(BMI)、类固醇使用史和合并症与PSH发展的关系。中位随访时间为36个月(0 ~ 99个月)。结果:随访期间,50例患者发生PSH, Kaplan-Meier法5年PSH累计发病率为37.8%。多因素COX分析中,女性(风险比[HR], 3.29;95%置信区间[CI], 1.77 ~ 6.11;P < 0.0001),年龄大于60岁(HR, 2.37;95% CI, 1.26 ~ 4.46;P = 0.01), BMI大于25 kg/m(2) (HR, 1.8;95% CI, 1.02 ~ 3.16;P = 0.04),高血压(HR, 2.08;95% CI, 1.14 ~ 3.81;P = 0.02)均为PSH发生的独立危险因素。结论:PSH 5年发病率为37.8%。PSH的显著危险因素为:女性、年龄大于60岁、BMI大于25 kg/m(2)、高血压。当患者有这些因素时,在结肠造口形成时使用预防性补片可能是可取的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Incidence and risk factors of parastomal hernia.

Purpose: Among the various stoma complications, the parastomal hernia (PSH) is the most common. Prevention of PSH is very important to improve the quality of life and to prevent further serious complications. The aim of this study was to analyze the incidence and the risk factors of PSH.

Methods: From January 2002 and October 2008, we retrospectively reviewed 165 patients who underwent an end colostomy. As a routine oncologic follow-up, abdomino-pelvic computed tomography was used to examine the occurrence of the PSH. The associations of age, sex, body mass index (BMI), history of steroid use and comorbidities to the development of the PSH were analyzed. The median duration of the follow-up was 36 months (0 to 99 months).

Results: During follow-up, 50 patients developed a PSH and the 5-year cumulative incidence rate of a PSH, obtained by using the Kaplan-Meier method, was 37.8%. In the multivariate COX analysis, female gender (hazard ratio [HR], 3.29; 95% confidence interval [CI], 1.77 to 6.11; P < 0.0001), age over 60 years (HR, 2.37; 95% CI, 1.26 to 4.46; P = 0.01), BMI more than 25 kg/m(2) (HR, 1.8; 95% CI, 1.02 to 3.16; P = 0.04), and hypertension (HR, 2.08; 95% CI, 1.14 to 3.81; P = 0.02) were all independent risk factors for the development of a PSH.

Conclusion: The 5-year incidence rate of a PSH was 37.8%. The significant risk factors of a PSH were as follows: female gender, age over 60 years, BMI more than 25 kg/m(2), and hypertension. Using a prophylactic mesh during colostomy formation might be advisable when the patients have these factors.

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