[抗体及其作为免疫酶分析工具的作用]。

Q4 Medicine Revista Cubana de Medicina Tropical Pub Date : 2010-05-01
Anselmo J Otero González
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引用次数: 0

摘要

本文介绍了自抗体被发现以来的历史和演变。它还阐明了它们复杂的结构和功能,这些结构和功能在特定的时间内作为方法论基础,创造了难以想象的范式,如精细识别特异性,也破坏了其他表面上不可变的范式,如细胞基因组的不变性和普遍性。本文综述了基于抗原-抗体反应的分析系统的发展历程、传染病的现状以及传染病病原检测和监测在传染病控制中的决定性作用。抗体区分抗原相似结构的非凡能力使它们成为免疫测定的基本工具,也是目前一门成熟的学科,即免疫技术。
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[The antibodies and their role as analytic tools in immunoenzymatic assays].

This paper presented the history and evolution of the antibodies since their discovery. It also elucidated their complex structure and function that have served at a given time as methodological basis for creating unimaginable paradigms such as fine recognition specificity, and also for destroying other apparently immutable ones as invariability and universality of the cellular genome. A review was made of the evolution of antigen-antibody reaction-based analytical systems up to the present, the situation of infectious diseases and the determining role that detection and monitoring of infectious agents play in their control. The extraordinary capability of antibodies to discriminate antigenically similar structures allows them to be fundamental tools in immunoassays and also in a well-established discipline at present, that is, immunotechnology.

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来源期刊
Revista Cubana de Medicina Tropical
Revista Cubana de Medicina Tropical Medicine-Infectious Diseases
CiteScore
0.30
自引率
0.00%
发文量
0
期刊介绍: La Revista Cubana de Medicina Tropical tiene la misión de publicar artículos científicos especializados en medicina tropical, microbiología, parasitología, epidemiología y otras especialidades afines. Se distribuye directamente por el editor a los suscriptores en formato impreso (ISSN 0375-0760). Está dirigida a profesionales y técnicos en el campo de la medicina tropical, microbiología, parasitología y epidemiología. Recibe contribuciones en idioma español, inglés y portugués sin distinción en el país de procedencia.
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