肯尼亚西部moi教学和转诊医院甲状腺疾病患者甲状腺激素和血液学指标水平。

ISRN endocrinology Pub Date : 2013-04-15 Print Date: 2013-01-01 DOI:10.1155/2013/385940
M A Iddah, B N Macharia, A G Ng'wena, A Keter, A V O Ofulla
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引用次数: 42

摘要

问题陈述。甲状腺疾病在肯尼亚西部很普遍,但疾病对甲状腺激素和血液学指标水平的影响尚未有文献记载。研究人口。2008年1月至2011年12月期间在MTRH接受甲状腺疾病治疗的患者。目标。目的:测定肯尼亚西部MTRH甲状腺疾病患者甲状腺激素和血液学指标水平。方法。一项回顾性研究,其中患者资料和存储的患者样本,谁提出了甲状腺病变,甲状腺切除术,并进行了组织学检查。分析促甲状腺激素(TSH)、甲状腺素(T4)和三碘甲状腺原氨酸(T3)血液水平、白细胞(wbc)、红细胞(rbc)、血小板计数和血红蛋白(Hb)水平。结果。男女比例为1:10.9,其中女性368人(95%)。中位年龄41岁(IQR: 32-48岁),年龄范围14-89岁。h免疫性甲状腺疾病患者激素水平较高(P = 0.0232;30-39岁的人,TSH和T3分别为0.040)。免疫性甲状腺疾病患者wbc、rbc、HGB、血小板差异无统计学意义,P值分别为0.547、0.205、0.291、0.488。结论。甲状腺疾病低红细胞贫血与甲状腺激素无显著相关性,P值为0.512。
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Thryroid hormones and hematological indices levels in thyroid disorders patients at moi teaching and referral hospital, Western kenya.

Problem Statement. Thyroid disorders are prevalent in western Kenya, but the effects of disorders on thyroid hormones and hematological indices levels have not been documented. Study Population. Patients treated for thyroid disorders at the MTRH between January 2008 and December 2011. Objectives. To determine the thyroid hormones and hematological indices levels in thyroid disorders patients at the MTRH, western Kenya. Methodology. A retrospective study in which patient data and stored samples of patients, who presented with thyroid pathologies, underwent thyroidectomy, and histological examinations are done. Thyroid stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3) blood levels, white blood cells (WBCs), red blood cells (RBCs), platelet counts, and hemoglobin (Hb) levels were analyzed. Results. Male : female ratio was 1 : 10.9 with female representing 368 (95%). The median age was 41 (IQR: 32-48) with a range of 14-89 years. HHormonal levels for immunological thyroid disease patients were higher (P = 0.0232; 0.040) for TSH and (T3) for those aged 30-39 years, respectively. The WBCs, RBCs, HGB, and platelets in immunological thyroid disease were not statistically significant with P values of 0.547, 0.205, 0.291, and 0.488 respectively. Conclusion. The presence of anaemia due to low RBCs in thyroid disease is not significantly associated with thyroid hormone with a P value of 0.512.

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