Carmelo Capula, Eusebio Chiefari, Anna Vero, Stefania Iiritano, Biagio Arcidiacono, Luigi Puccio, Vittorio Pullano, Daniela Foti, Antonio Brunetti, Raffaella Vero
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引用次数: 25
摘要
产后筛查对于早期诊断为妊娠期糖尿病(GDM)的2型糖尿病妇女至关重要。然而,它的利率仍然低得令人失望。因此,我们计划在咨询前后检查意大利GDM妇女的产后糖耐量试验(ppOGTT)率,并确定依从性的人口统计学、临床和/或生化预测指标。为了达到这些目的,我们回顾性地在2004年至2011年间在意大利南部卡拉布里亚招募了1159名患有GDM的女性。在过去的一年中,对后续行动的重要性进行了口头和书面咨询。数据采用多元回归分析。引入咨询后,观察到复诊率显著增加[调整优势比(AOR) 5.17 (95% CI, 3.83-6.97), P < 0.001]。有趣的是,以前诊断多囊卵巢综合征(PCOS)成为产后随访的主要预测因素[AOR 5.27 (95% CI, 3.51-8.70), P < 0.001],即使在没有咨询的分层后也是如此。既往GDM诊断、高等教育程度和胰岛素治疗也是相关的预测因素。总的来说,我们的数据表明,咨询干预是有效的,即使许多妇女未能返回,而多囊卵巢综合征代表了一个新的强有力的预测坚持产后检查。
Predictors of postpartum glucose tolerance testing in italian women with gestational diabetes mellitus.
Postpartum screening is critical for early identification of type 2 diabetes in women previously diagnosed with gestational diabetes mellitus (GDM). Nevertheless, its rate remains disappointingly low. Thus, we plan to examine the rate of postpartum glucose tolerance test (ppOGTT) for Italian women with GDM, before and after counseling, and identify demographic, clinical, and/or biochemical predictors of adherence. With these aims, we retrospectively enrolled 1159 women with GDM, in Calabria, Southern Italy, between 2004 and 2011. During the last year, verbal and written counseling on the importance of followup was introduced. Data were analyzed by multiple regression analysis. A significant increase of the return rate was observed following introduction of the counseling [adjusted odds ratio (AOR) 5.17 (95% CI, 3.83-6.97), P < 0.001]. Interestingly, previous diagnosis of polycystic ovary syndrome (PCOS) emerged as the major predictor of postpartum followup [AOR 5.27 (95% CI, 3.51-8.70), P < 0.001], even after stratification for the absence of counseling. Previous diagnosis of GDM, higher educational status, and insulin treatment were also relevant predictors. Overall, our data indicate that counseling intervention is effective, even if many women fail to return, whereas PCOS represents a new strong predictor of adherence to postpartum testing.