丹麦和西班牙全科医生诊断肺炎的显著差异:一项横断面研究。

Sarah Friis Christensen, Lars Christian Jørgensen, Gloria Cordoba, Carl Llor, Volkert Siersma, Lars Bjerrum
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引用次数: 16

摘要

背景:在下呼吸道感染(LRTIs)患者中,确定谁应该使用抗生素治疗是一个挑战。根据国际准则,对疑似肺炎的患者应开抗生素,而急性支气管炎被认为是一种病毒感染,一般不应用抗生素治疗。下呼吸道感染患者肺炎的过度诊断可能导致抗生素的过度使用。目的:调查两个抗生素处方率不同的国家(丹麦和西班牙)LRTI患者推定肺炎的患病率,并比较全科医生在选择诊断肺炎而不是急性支气管炎时,哪些症状和临床检查最重要。方法:作为欧盟资助的HAPPY AUDIT项目的一部分,对来自丹麦和西班牙的全科医生进行了横断面研究。共纳入2698例下呼吸道感染患者。结果:在丹麦,47%的下呼吸道感染患者被诊断为肺炎,而西班牙的这一比例为11%。在西班牙,发烧和x线阳性在肺炎诊断中的权重明显高于丹麦。而丹麦gp更重视呼吸困难/呼吸急促和c反应蛋白水平>50mg/L。肺炎的其他典型症状均无显著影响。结论:我们的研究结果表明,全科医生对肺炎的诊断标准在丹麦和西班牙之间存在很大差异。丹麦下呼吸道感染患者中肺炎的高患病率可能表明肺炎的过度诊断,这反过来又可能导致抗生素的过度使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Marked differences in GPs' diagnosis of pneumonia between Denmark and Spain: a cross-sectional study.

Background: In patients with lower respiratory tract infections (LRTIs) it is a challenge to identify who should be treated with antibiotics. According to international guidelines, antibiotics should be prescribed to patients with suspected pneumonia while acute bronchitis is considered a viral infection and should, generally, not be treated with antibiotics. Overdiagnosis of pneumonia in patients with LRTIs may lead to antibiotic overprescribing.

Aims: To investigate the prevalence of presumed pneumonia in patients with LRTI in two countries with different antibiotic prescribing rates (Denmark and Spain) and to compare which symptoms and clinical tests are of most importance for the GP when choosing a diagnosis of pneumonia rather than acute bronchitis.

Methods: A cross-sectional study including GPs from Denmark and Spain was conducted as part of the EU-funded project HAPPY AUDIT. A total of 2,698 patients with LRTI were included.

Results: In Denmark, 47% of the patients with LRTI were classified with a diagnosis of pneumonia compared with 11% in Spain. In Spain, fever and a positive x-ray weighted significantly more in the diagnosis of pneumonia than in Denmark. Danish GPs, however, attached more importance to dyspnoea/polypnoea and C-reactive protein levels >50mg/L. None of the other typical symptoms of pneumonia had a significant influence.

Conclusions: Our results indicate that GPs' diagnostic criteria for pneumonia differ substantially between Denmark and Spain. The high prevalence of pneumonia among Danish patients with LRTI may indicate overdiagnosis of pneumonia which, in turn, may lead to antibiotic overprescribing.

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来源期刊
Primary Care Respiratory Journal
Primary Care Respiratory Journal PRIMARY HEALTH CARE-RESPIRATORY SYSTEM
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