强化尿液分析在妊娠无症状细菌性尿症检测中的应用。

E O S Aigere, B O Okusanya, J O Eigbefoh, G B O Okome
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引用次数: 0

摘要

背景:妊娠期无症状性细菌尿(ASB)的检测和治疗对于避免伴随的母体和胎儿发病率非常重要。除了尿培养,没有其他筛查试验是明确的。目的:探讨应用强化尿分析试验检测妊娠期ASB的方法。方法:这是一项前瞻性观察研究,将增强尿液分析与试纸试验和尿液培养进行比较。对连续150例无症状孕妇采集干净的中游尿液标本。采用效度检验进行比较。结果:强化尿液分析检出的细菌尿与尿液培养检出的细菌尿相同(4% vs. 4.7%)。敏感性为57.1%,特异性为98.6%。与尿培养相比,假阴性率为42.9%,准确率为96.7%。增强尿液分析需要1-2小时,需要使用显微镜的技能,比试纸尿液分析更昂贵。结论:增强尿液分析的准确性及其检测ASB的能力与尿液培养一样多,这意味着它可以用于检测妊娠无症状细菌尿,尽管由于成本和技术问题,只能在二级和三级卫生中心使用。
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Enhanced urinalysis in the detection of asymptomatic bacteriuria in pregnancy.

Background: Detection and treatment of asymptomatic bacteriuria (ASB) in pregnancy is important to avert the attendant maternal and fetal morbidity. Other than urine culture, no other screening test is unequivocal.

Objective: The use of enhanced urinalysis test to detect ASB in pregnancy was investigated.

Methods: This was a prospective observational study which compared enhanced urinalysis with dipstick tests and urine culture. Clean catch midstream urine specimen was collected from 150 consecutive asymptomatic pregnant women. Tests of validity were used for comparison.

Results: Enhanced urinalysis detected bacteriuria as much as urine culture (4% vs. 4.7%). Itwas 57.1% sensitive and 98.6% specific. It had a false negative rate of 42.9% and was 96.7% accurate when compared to urine culture. Enhanced urinalysis took 1-2 hours to be done and required skills to use the microscope and was more expensive than dipstick urinalysis.

Conclusion: The accuracy of enhanced urinalysis and its ability to detect ASB as much as urine culture connotes that it can be used to detect asymptomatic bacteriuria in pregnancy albeit only in secondary and tertiary health centres because of the cost and technicality involved.

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