利用人工智能技术识别独特的重复模式,定位DNA指纹中的突变。

B Mukunthan, N Nagaveni
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引用次数: 4

摘要

在基因工程中,法医科学家利用传统的技术和算法,根据各自的DNA图谱来协助识别个体,涉及更复杂的计算步骤和数学公式,而且在实验室中识别基因组序列中的突变位置仍然是一项紧迫的任务。这种新颖的方法提供了解决没有算法解决方案的问题的能力,并且可用的解决方案也太复杂而难以找到。生物信息学和神经网络技术的完美结合,产生了高效的DNA模式分析算法,预测精度最高。
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Identification of unique repeated patterns, location of mutation in DNA finger printing using artificial intelligence technique.

In genetic engineering, conventional techniques and algorithms employed by forensic scientists to assist in identification of individuals on the basis of their respective DNA profiles involves more complex computational steps and mathematical formulae, also the identification of location of mutation in a genomic sequence in laboratories is still an exigent task. This novel approach provides ability to solve the problems that do not have an algorithmic solution and the available solutions are also too complex to be found. The perfect blend made of bioinformatics and neural networks technique results in efficient DNA pattern analysis algorithm with utmost prediction accuracy.

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来源期刊
International Journal of Bioinformatics Research and Applications
International Journal of Bioinformatics Research and Applications Health Professions-Health Information Management
CiteScore
0.60
自引率
0.00%
发文量
26
期刊介绍: Bioinformatics is an interdisciplinary research field that combines biology, computer science, mathematics and statistics into a broad-based field that will have profound impacts on all fields of biology. The emphasis of IJBRA is on basic bioinformatics research methods, tool development, performance evaluation and their applications in biology. IJBRA addresses the most innovative developments, research issues and solutions in bioinformatics and computational biology and their applications. Topics covered include Databases, bio-grid, system biology Biomedical image processing, modelling and simulation Bio-ontology and data mining, DNA assembly, clustering, mapping Computational genomics/proteomics Silico technology: computational intelligence, high performance computing E-health, telemedicine Gene expression, microarrays, identification, annotation Genetic algorithms, fuzzy logic, neural networks, data visualisation Hidden Markov models, machine learning, support vector machines Molecular evolution, phylogeny, modelling, simulation, sequence analysis Parallel algorithms/architectures, computational structural biology Phylogeny reconstruction algorithms, physiome, protein structure prediction Sequence assembly, search, alignment Signalling/computational biomedical data engineering Simulated annealing, statistical analysis, stochastic grammars.
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