1999-2011年法罗群岛、冰岛和丹麦的抗菌药物使用情况。

Marita Debess Magnussen, Thorolfur Gudnason, Ulrich Stab Jensen, Niels Frimodt-Møller, Karl G Kristinsson
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引用次数: 5

摘要

背景:法罗群岛、冰岛和丹麦是邻近的北欧国家,在民族、文化和政治上有很大的相似性,而且相对来说是同质的。通过比较这些国家的抗菌药物使用情况,可以获得关于处方做法的重要信息。目的是描述、比较和分析这些国家1999-2011年期间全身性抗菌药物的使用情况。方法:从法罗群岛、冰岛和丹麦获得系统抗菌药物使用的数据,并以限定日剂量(DDD)表示。还获得了特定年龄组的处方数据。结果:3国1999-2011年抗菌药物总使用量差异显著,冰岛平均使用量为21.8 DDD/1000居民/天,法罗群岛为17.7 DDD/1000居民/天,丹麦为16.3 DDD/1000居民/天。法罗群岛和冰岛的总使用量多年来保持相当稳定,而丹麦的使用量从1999年的13.5 DID逐渐增加到2011年的19.5 DID。冰岛的高使用率可以用四环素的高消费量来解释。各国在使用个别青霉素类和大环内酯类药物方面也存在相当大的差异。结论:尽管这三个国家在种族和文化上有很大的相似性,但我们发现在抗菌药物的总使用上存在显著差异,在单个抗菌药物的使用上存在重要差异。
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Antibacterial use in the Faroe Islands, Iceland, and Denmark 1999-2011.

Background: The Faroe Islands, Iceland, and Denmark are neighbouring Nordic countries with great ethnic, cultural, and political similarities and are relatively homogeneous. Important information about prescribing practices can be obtained by comparing the antibacterial use in these countries. The objective was to describe, compare, and analyse the use of systemic antibacterial agents in these countries during the y 1999-2011.

Methods: Data were obtained from the Faroe Islands, Iceland, and Denmark on systemic antibacterial use and expressed in defined daily dosages (DDD). Prescription data were also obtained for specific age groups.

Results: The total antibacterial use for the y 1999-2011 varied markedly between the 3 countries, with a mean use of 21.8 DDD/1000 inhabitants/day (DID) in Iceland, 17.7 in the Faroe Islands, and 16.3 in Denmark. The total use remained fairly constant over the years in the Faroe Islands and Iceland, whereas in Denmark it increased gradually from 13.5 DID in 1999 to 19.5 DID in 2011. The higher use in Iceland can be explained by much higher consumption of tetracyclines. There was also considerable variation in the use of individual penicillins and macrolides between the countries.

Conclusions: Despite the great ethnic and cultural similarities of these 3 countries, we found marked differences in total antibacterial use and important differences in the use of individual antibacterials.

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