运动与妊娠期糖尿病。

Medicine and sport science Pub Date : 2014-01-01 Epub Date: 2014-09-09 DOI:10.1159/000357340
Mireille N M van Poppel, Stephanie-May Ruchat, Michelle F Mottola
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引用次数: 14

摘要

妊娠期糖尿病(GDM)被定义为“碳水化合物不耐受导致不同严重程度的高血糖,在妊娠期间发病或首次发现”。妊娠糖尿病与怀孕和分娩期间母亲和婴儿的几种有害健康后果有关。GDM最大的公共卫生影响是通过其对母亲未来的糖尿病和后代的肥胖和糖尿病的作用。鉴于体育活动在预防和治疗2型糖尿病方面的已知有效性,体育活动(PA)可能是预防和治疗GDM的有效干预措施。根据观察性研究,在怀孕前和/或怀孕期间开始的PA对母体葡萄糖和胰岛素代谢有积极影响,并降低GDM的风险。然而,尽管有报道称PA干预可以有效改善已经发生GDM的妇女的血糖控制,但旨在预防GDM的产前PA干预在增加PA水平方面显示出适度的效果,因此对改善葡萄糖/胰岛素代谢或降低GDM发病率无效。因此,迫切需要制定有效的策略来增加PA水平,特别是对于经常肥胖和不运动的GDM高危妇女。预防或管理GDM的最佳干预措施尚不清楚,需要进一步的研究来确定最成功的PA干预的类型、强度、频率和持续时间。此外,PA对新生儿结局的影响尚不清楚,强烈建议未来的研究检查更具体的新生儿结局,如身体成分。
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Physical activity and gestational diabetes mellitus.

Gestational diabetes mellitus (GDM) is defined as 'carbohydrate intolerance resulting in hyperglycemia of variable severity with onset or first recognition during pregnancy'. GDM is associated with several detrimental health consequences during pregnancy and delivery for both mother and baby. The largest public health impact of GDM is through its role on future diabetes in the mother and obesity and diabetes in the offspring. Physical activity (PA) is likely an effective intervention for prevention and treatment of GDM, given its known effectiveness in prevention and treatment of type 2 diabetes. Based on observational studies, PA initiated before and/or during pregnancy has a positive influence on maternal glucose and insulin metabolism and reduces the risk of GDM. However, although PA interventions have been reported to be effective at improving glycemic control in women who already developed GDM, prenatal PA interventions aimed at preventing GDM have shown modest effectiveness in increasing PA levels and thus were not effective in improving glucose/insulin metabolism or reducing GDM incidence. There is therefore a strong need to develop effective strategies for increasing PA levels, especially in women at high risk for GDM who are often obese and inactive. The optimal intervention for preventing or managing GDM is still unknown, and further studies are needed to determine the type, intensity, frequency and duration for the most successful PA intervention. Furthermore, the effects of PA on neonatal outcomes are not clear, and it is highly recommended that future studies examine more specific neonatal outcomes such as body composition.

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