坏死梭杆菌引起的脓毒性颈内静脉血栓形成,由断针介导。

George Galyfos, Konstantinos Palogos, Nikolaos Kavouras
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引用次数: 1

摘要

将药物注射到颈部是不寻常的,颈内静脉血栓形成是一种罕见的临床表现,具有严重并发症的高风险。我们报告一例31岁男性静脉注射毒品使用者表现为发烧,呼吸短促和右颈部水肿。实验室研究显示炎症参数升高。x射线成像显示颈部软组织内有一根破损的注射器针头。胸部和脑部CT扫描未见明显异常,而颈部CT显示右侧颈内静脉血栓形成。开始静脉注射抗生素,并在鉴定出革兰氏阴性厌氧口咽源病原体(坏死性梭杆菌)后进行修改。经治疗症状缓解后出院。脓毒性颈内静脉血栓形成应始终纳入局部颈部炎症和全身败血症的鉴别诊断静脉吸毒者。及时和积极的抗生素治疗是至关重要的,而抗凝治疗的作用尚不明确。
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Septic internal jugular vein thrombosis caused by Fusobacterium necrophorum and mediated by a broken needle.

The injection of drugs into the neck is unusual and thrombosis of the internal jugular vein can be a rare clinical presentation with a high risk for severe complications. We report a case of a 31-year-old male intravenous drug user presenting with fever, shortness of breath and right neck oedema. Laboratory studies revealed elevated inflammation parameters. X-ray imaging revealed a broken syringe needle inside the soft tissues of the neck. Computed tomography (CT) scans of the thorax and brain were unremarkable, while cervical CT showed a fully thrombosed, right internal jugular vein. Intravenous antibiotics were initiated, and modified after identification of an anaerobic Gram-negative oropharynx-derived pathogen (Fusobacterium necrophorum). The patient was discharged after resolution of symptoms under treatment. Septic internal jugular vein thrombosis should always be included in the differential diagnosis of local neck inflammation and systemic sepsis in intravenous drug users. Prompt and aggressive antibiotic treatment is vital, whereas the role of anticoagulation therapy is not definitely known.

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