子宫颈腺泡软组织肉瘤:病例报告和文献综述。

Korean Journal of Pathology Pub Date : 2014-10-01 Epub Date: 2014-10-27 DOI:10.4132/KoreanJPathol.2014.48.5.361
Hyun Ju Lee
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引用次数: 0

摘要

子宫颈腺泡软组织肉瘤(ASPS)是一种罕见的恶性肿瘤,各种语言的文献已报道了 21 例(包括我们的病例)。在此,我们描述了一名 17 岁女性患者的病例,她因活动性阴道出血而就诊。盆腔检查发现一个 1.6×1.0×0.5 厘米大小的软肿块突出于子宫颈。最终病理诊断为宫颈 ASPS。免疫组化结果显示,肿瘤细胞核转录因子E3呈强阳性。患者在未接受辅助治疗的情况下,保持无病状态达 24 个月之久。宫颈 ASPS 的预后要比软组织 ASPS 的预后好得多,因为它临床发现早、体积小、可切除。在鉴别诊断异常上皮样肿瘤时,尤其是在年轻女性中,应考虑到ASPS,这种肿瘤表现为器官样外观,细胞学不典型性轻微,无/罕见有丝分裂像。病理学家应注意ASPS可能起源的异常部位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Alveolar soft part sarcoma of the uterine cervix: a case report and review of the literature.

Alveolar soft part sarcoma (ASPS) of the uterine cervix is a rare malignancy, and 21 cases have been reported the literature from every language (including our case). Herein, we describe a 17-yearold female patient who presented with active vaginal bleeding. Pelvic examination revealed a 1.6 ×1.0×0.5-cm-sized soft mass protruding from the uterine cervix. The final pathological diagnosis was ASPS of the uterine cervix. Immunohistochemically, tumor cells were strongly nuclear positive for transcription factor E3. The patient remained disease free for 24 months without adjuvant therapy. The prognosis of ASPS in the cervix is considerably better than that of ASPS in soft tissues due to early clinical detection, small size, and resectability. ASPS should be considered in the differential diagnosis of an unusual epithelioid neoplasm showing organoid appearance with mild cytologic atypia and no/rare mitotic figures, particularly in young women. Pathologists should be aware of those unusual locations where ASPS may originate.

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来源期刊
Korean Journal of Pathology
Korean Journal of Pathology 医学-病理学
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审稿时长
6-12 weeks
期刊最新文献
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