鸟类肺:15例临床放射学表现。

Raj Kumar, Mandeep Singh
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引用次数: 28

摘要

鸟类爱好者肺(BFL)是一种对禽类抗原(通常是吸入鸟类羽毛和粪便中的蛋白质)的反应而发生的超敏性肺炎。诊断是基于临床、放射学和活检特征的结合。本研究旨在强调BFL病例的临床放射学表现。材料与方法:本研究回顾性分析了Vallabhbhai Patel胸科研究所(Vallabhbhai Patel Chest Institute)某单位2013-2014年两年间诊断出的鸟类爱好者肺病例。分析受试者的临床放射学特征。BFL的诊断依据Mark Schuyler和Yvon Cormier制定的标准。结果:研究期间共确诊BFL 15例,其中女性12例,男性3例,平均年龄54.93±14.21岁。所有的研究对象都有明显的鸽子接触史,而且都不吸烟。症状出现前的时间从1年到8年不等。发病时主要症状为用力性呼吸困难和咳嗽。影像学上可见弥漫性小叶中心结节,磨玻璃样病变-上叶弥漫性或斑片状为主,纤维化伴或不伴牵引性支气管扩张,蜂窝状和纵隔淋巴结病。支气管镜检查显示肉芽肿及慢性间质炎。结论:BFL可表现出广泛的放射学模式,必须保持高度的怀疑指数,特别注意每例间质性肺疾病的详细暴露史。
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Bird fancier's lung: clinical-radiological presentation in 15 cases.

Introduction: Bird fancier's lung (BFL) is a type of hypersensitivity pneumonitis occurring in response to avian antigens (usually inhaled proteins in bird feathers and droppings). The diagnosis is based on a combination of clinical, radiological, and biopsy characteristics. The present study was planned to highlight the clinico-radiological presentation in cases of BFL.

Material and methods: The present study is a retrospective analysis of cases of bird fancier's lung diagnosed in a unit of Vallabhbhai Patel Chest Institute over a period of two years, from 2013-2014. The clinico-radiological features of the subjects were analysed. The diagnosis of BFL was made as per criteria laid down by Mark Schuyler and Yvon Cormier.

Results: There were a total of fifteen cases diagnosed with BFL during the study period, comprising twelve females and three males with a mean age of 54.93 ± 14.21 years. All the studied subjects gave significant history of exposure to pigeons and were non-smokers. The period of symptoms prior to presentation varied from one to eight years. The main symptoms on presentation were exertional breathlessness and cough. Radiologically, diffuse centrilobular nodules, ground glassing - diffuse or patchy predominant in upper lobes, fibrosis with or without traction bronchiectasis, honeycombing, and mediastinal lymphadenopathy were seen. Bronchoscopy showed ill-defined granulomas and chronic interstitial inflammation.

Conclusions: BFL can exhibit a wide range of radiological patterns, and a high index of suspicion must be maintained, with particular attention to detailed exposure history in every case of interstitial lung disease.

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