分析侧对侧相关吻合策略和动脉补片。

Q3 Medicine Open Biomedical Engineering Journal Pub Date : 2015-02-27 eCollection Date: 2015-01-01 DOI:10.2174/1874120701509010001
P C Roussis, A E Giannakopoulos, H P Charalambous
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引用次数: 2

摘要

缝线应力集中和内膜增生与端侧吻合和侧侧吻合的远期并发症有关。几个因素,如血液动力学效应,生物活性和血管的机械性能,确定影响问题。然而,目前尚不完全清楚哪些因素影响最严重的长期并发症,以及以何种具体方式影响。本研究旨在探讨弹性(顺应性)失配是否会增加缝合线处的应力集中和内膜增厚。使用与宿主动脉具有相似机械特性的移植物或使用静脉贴片和袖带的吻合技术(Taylor-patch和Miller-cuff吻合)可以获得更好的顺应性。本研究中使用的吻合模型是由两个半圆柱体组成的圆筒形系统,通过两个铰链相互连接。内压作用在动脉壁上。静态和动态响应是根据径向和切向位移、内力和两根血管的应变及其截面的旋转来解析导出的。结果表明,动脉与移植物之间的弹性失配增加可能会由于连接处的大不相容角而促进内膜增厚,而缝合线处的弹性失配与应力集中升高之间没有相关性。本模型的另一个有趣的应用是在颈动脉内膜切除术中应用的动脉修补。
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Analytical Side-to-Side Related Anastomotic Strategies and Artery Patching.

Suture line stress concentration and intimal hyperplasia are related to the long-term complications of end-toside and side-to-side anastomosis. Several factors, such as hemodynamic effects, biological activities and the mechanical properties of the blood vessels, are identified to influence the problem. Yet, it is not completely clear which are the factors that influence most the long-term complications and in what specific way. This study aims to examine if elastic (compliance) mismatch increases the stress concentration and intimal thickening at the suture line. Better compliance may be obtained by using grafts with similar mechanical properties to the host artery or by anastomosis techniques that utilize vein patches and cuffs (Taylor-patch and Miller-cuff anastomosis). The anastomosis model used in this study is a circular cylindrical system consisting of two semi-cylinders, interconnected by two hinges. The internal blood pressure is applied on the arterial walls. The static and dynamic responses are analytically derived in terms of radial and tangential displacements, internal forces and strains of the two blood vessels and rotation of their cross-section. Results suggest that increased elastic mismatch between the artery and the graft may promote elevated intimal thickening due to large incompatible angles at the junction, whereas there is no correlation between elastic mismatch and elevated stress concentration at the suture line. Another interesting application of the present model is the patching of arteries as applied in carotid endarterectomy.

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来源期刊
Open Biomedical Engineering Journal
Open Biomedical Engineering Journal Medicine-Medicine (miscellaneous)
CiteScore
1.60
自引率
0.00%
发文量
4
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