乳房 X 射线照相术假阳性的等待时间和社会心理后果:队列研究。

Bruno Heleno, Volkert Siersma, John Brodersen
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摘要

背景:乳房 X 射线检查假阳性的社会心理反应差异很大。我们的目的是评估妇女需要等待更长时间才能排除癌症是否会增加社会心理后果,这种后果在排除癌症后是否会持续存在:我们选取了在哥本哈根和富能(丹麦)接受为期一年的乳腺癌筛查的乳腺 X 射线假阳性妇女(n = 272)。我们在妇女接受回访前以及接受最终诊断后的 1、6、18 和 36 个月测量了她们的社会心理后果。在妇女被告知癌症已被排除后,不良的社会心理后果随着时间的推移而减少。我们发现,在 5 个时间点(癌症排除后的 0、1、6、18 和 36 个月)通过特定情况问卷(乳腺癌筛查后果)测量社会心理后果时,在复诊时立即排除癌症的妇女(等待时间为 0)和需要等待更长时间才能排除癌症的妇女(等待时间为 1-30、30-120 和大于 120 天)之间没有统计学意义上的显著差异:我们没有证实等待时间与较差的长期社会心理后果有关,但II型误差(未能检测到真正的差异)可能是我们的结果的一个合理解释。
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Waiting time and the psychosocial consequences of false-positive mammography: cohort study.

Background: There is wide variation in the psychosocial response to false-positive mammography. We aimed to assess whether women having to wait longer to exclude cancer had increased psychosocial consequences that persisted after cancer was ruled out.

Findings: We selected women with false-positive mammography (n = 272), screened for breast cancer in Copenhagen and Funen (Denmark) over a 1-year period. We measured psychosocial consequences immediately before women attended their recall visit and 1, 6, 18 and 36 months after women received their final diagnosis. After women were told that cancer had been ruled out, adverse psychosocial consequences decreased with time. We found no statistically significant differences between women who had cancer ruled out immediately at the recall visit (waiting time of 0) and women who had to wait longer before cancer was ruled out (waiting times 1-30, 30-120 and > 120 days), when psychosocial consequences were measured via a condition-specific questionnaire (Consequences of Screening in Breast Cancer) at 5 time points (0, 1, 6, 18 and 36 months after cancer exclusion).

Conclusion: We did not confirm that waiting time was associated with worse long-term psychosocial consequences but type II error (failure to detect a true difference) might be a plausible explanation for our results.

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