中国儿童白内障住院10年病因学回顾。

眼科学报 Pub Date : 2014-09-01
Zixun Song, Daixin Zhao, Cancan Lv, Wei Pu, Wei Xiao
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引用次数: 0

摘要

目的:我们的目的是更好地了解在中国单一医院治疗的儿童白内障的病因和特征。方法:回顾性分析中国医科大学附属盛京医院2003年8月至2013年7月10年间的医疗记录,确定所有治疗不同亚型儿童白内障的患者。建立了一个包含367名14岁以下受试者(598名,包括第二轮手术)的数据库。结果:在该队列中(n = 367;男性:232人,占63.2%;女性135例(36.8%),双侧白内障200例(54.5%),3岁以下258例(70.3%)。在所有年龄组和所有儿童白内障亚型中,男性最常受影响。先天性白内障是最常见的亚型,占296例(80.7%)。大多数先天性白内障伴有其他眼部或全身异常;48例(16.22%)为遗传性。外伤性白内障是获得性白内障中最常见的亚型(85.92%)。少数由类固醇(n = 3)或代谢紊乱(n = 2)引起的白内障发生在男性中,并累及双眼。结论:本组儿童白内障以先天性白内障居多。中国婴儿的眼科评估明显滞后,应通过教育儿童和家长了解白内障发展的危险因素来解决这一问题。对长期接受全身性类固醇治疗的儿童进行定期评估尤为重要。
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Ten-year etiologic review of Chinese children hospitalized for pediatric cataracts.

Purpose: Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.

Methods: Medical records accrued over a 10-year period (from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively, identifying all patients treated for various subtypes of pediatric cataract. A database with 367 subjects under 14 years of age (598, including second-round surgeries) was generated.

Results: Of this cohort (n = 367; males: 232, 63.2%; females: 135, 36.8%), 200 patients (54.5%) had bilateral cataracts, and 258 (70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract, males were most commonly affected. Congenital cataract was the most prevalent subtype, accounting for 296 patients (80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities; and in 48 patients (16.22%), they were hereditary. Traumatic cataract was the most common subtype (85.92%) of acquired cataract. The few instances of cataracts due to steroids (n = 3) or to metabolic disorders (n = 2) occurred in males and involved both eyes.

Conclusion: The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.

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来源期刊
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期刊介绍: Eye science was founded in 1985. It is a national medical journal supervised by the Ministry of Education of the People's Republic of China, sponsored by Sun Yat-sen University, and hosted by Sun Yat-sen University Zhongshan Eye Center (in October 2020, it was changed from a quarterly to a monthly, with the publication number: ISSN: 1000-4432; CN: 44-1119/R). It is edited by Ge Jian, former dean of Sun Yat-sen University Zhongshan Eye Center, Liu Yizhi, director and dean of Sun Yat-sen University Zhongshan Eye Center, and Lin Haotian, deputy director of Sun Yat-sen University Zhongshan Eye Center, as executive editor. It mainly reports on new developments and trends in the field of ophthalmology at home and abroad, focusing on basic research in ophthalmology, clinical experience, and theoretical knowledge and technical operations related to epidemiology. It has been included in important databases at home and abroad, such as Chemical Abstract (CA), China Journal Full-text Database (CNKI), China Core Journals (Selection) Database (Wanfang), and Chinese Science and Technology Journal Database (VIP).
期刊最新文献
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