结节性硬化症患者视网膜星形细胞错构瘤的影像特征。

眼科学报 Pub Date : 2014-12-01

Peng Zhang, Dongjie Sun, Jinting Zhu, Juan Li, Yusheng Wang

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引用次数: 0

摘要

目的:描述35岁男性结节性硬化症(TSC)患者视网膜星形细胞错构瘤的影像特征。方法:眼底摄影、眼底自体荧光(FAF)、眼底荧光素血管造影(FFA)、光谱域光学相干断层扫描(SD-OCT)检查该视网膜星形细胞错构瘤。结果:眼底摄影显示视网膜星形细胞错构瘤表现为边界清晰的桑葚样病变，由闪烁的淡黄色钙化球体组成。FAF显示密集的超自身荧光斑点，对应于视网膜星形细胞错构瘤。FFA显示错构瘤上方扩张的视网膜毛细血管渗漏。SD-OCT显示病变内虫蛀的光学空洞和高反射点。病变表面呈上下波动。结论:FAF是一种有用的成像方式，可以在视网膜星形细胞错构瘤和周围视网膜之间获得更大的对比，因为病变处的钙化高度自身荧光。FFA有利于监测病变血管的异常情况。SD-OCT能够可视化结构细节，如不均匀的表面和内部的高反射点。

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Image features of retinal astrocytic hamartoma in a patient with tuberous sclerosis complex.

Purpose: To describe the image features of retinal astrocytic hamartoma in a 35-year-old male patient with tuberous sclerosis complex (TSC).

Methods: Fundus photography, fundus autofluorescence (FAF), fundus fluorescein angiography (FFA), and spectral domain optical coherence tomography (SD-OCT) were performed for this retinal astrocytic hamartoma.

Results: Fundus photography showed that the retinal astrocytic hamartoma presented as a well-circumscribed, mulberry-like lesion consisting of glistening yellowish spherules of calcification. FAF demonstrated dense hyper-autofluorescence spots corresponding to retinal astrocytic hamartoma. FFA revealed leakage from dilated retinal capillaries over the hamartoma. SD-OCT indicated moth-eaten optically empty spaces and hyperreflective dots within the lesion. The lesion surface was fluctuate.

Conclusion: FAF is a useful imaging modality for obtaining greater contrast between a retinal astrocytic hamartoma and the surrounding retina due to hyper-autofluorescence of calcification in the lesion. FFA is beneficial for monitoring the abnormal blood vessels in these lesions. SD-OCT is capable of visualization the structural details, such as the uneven surface and inner hyperreflective dots.

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来源期刊

眼科学报

自引率

0.00%

发文量

1312

期刊介绍： Eye science was founded in 1985. It is a national medical journal supervised by the Ministry of Education of the People's Republic of China, sponsored by Sun Yat-sen University, and hosted by Sun Yat-sen University Zhongshan Eye Center (in October 2020, it was changed from a quarterly to a monthly, with the publication number: ISSN: 1000-4432; CN: 44-1119/R). It is edited by Ge Jian, former dean of Sun Yat-sen University Zhongshan Eye Center, Liu Yizhi, director and dean of Sun Yat-sen University Zhongshan Eye Center, and Lin Haotian, deputy director of Sun Yat-sen University Zhongshan Eye Center, as executive editor. It mainly reports on new developments and trends in the field of ophthalmology at home and abroad, focusing on basic research in ophthalmology, clinical experience, and theoretical knowledge and technical operations related to epidemiology. It has been included in important databases at home and abroad, such as Chemical Abstract (CA), China Journal Full-text Database (CNKI), China Core Journals (Selection) Database (Wanfang), and Chinese Science and Technology Journal Database (VIP).