{"title":"青少年特发性脊柱侧弯患者骨密度与骨代谢的关系。","authors":"Ko Ishida, Yoichi Aota, Naoto Mitsugi, Motonori Kono, Takayuki Higashi, Takuya Kawai, Katsutaka Yamada, Takanori Niimura, Kanichiro Kaneko, Hironori Tanabe, Yohei Ito, Tomoyuki Katsuhata, Tomoyuki Saito","doi":"10.1186/s13013-015-0043-x","DOIUrl":null,"url":null,"abstract":"<p><p>Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients. </p>","PeriodicalId":21722,"journal":{"name":"Scoliosis","volume":"10 ","pages":"19"},"PeriodicalIF":0.0000,"publicationDate":"2015-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13013-015-0043-x","citationCount":"9","resultStr":"{\"title\":\"Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis.\",\"authors\":\"Ko Ishida, Yoichi Aota, Naoto Mitsugi, Motonori Kono, Takayuki Higashi, Takuya Kawai, Katsutaka Yamada, Takanori Niimura, Kanichiro Kaneko, Hironori Tanabe, Yohei Ito, Tomoyuki Katsuhata, Tomoyuki Saito\",\"doi\":\"10.1186/s13013-015-0043-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients. </p>\",\"PeriodicalId\":21722,\"journal\":{\"name\":\"Scoliosis\",\"volume\":\"10 \",\"pages\":\"19\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s13013-015-0043-x\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scoliosis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13013-015-0043-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scoliosis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13013-015-0043-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis.
Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.
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