腔内近距离照射器的剂量学分析:一项实用研究。

IF 1.8 Q3 ONCOLOGY Radiation Oncology Journal Pub Date : 2022-09-01 Epub Date: 2022-09-08 DOI:10.3857/roj.2022.00199
Aijaz A Khan, Anuj Vijay, Shaqul Qamar Wani, Malik M Haq
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引用次数: 2

摘要

目的:腔内近距离放射治疗是妇科肿瘤治疗的重要方法之一。美国医学物理学家协会(AAPM)工作组第43号报告(TG-43)发布的剂量计算方法中没有考虑衰减的影响。在本研究中,我们使用Gafchromic薄膜和井型电离室测量了高剂量率(HDR)近距离照射器对剂量分布的影响。材料和方法:首先使用井型电离室和水等效弹性凝胶来收集电荷,执行处理计划系统创建的计划。同样,使用不同角度的中心串联与不同直径的阴道圆柱体执行相同的计划,并测量电荷收集。对于体外剂量测量,该计划也在串联和阴道圆柱体组合上执行,阴道圆柱体表面固定有Gafchromic膜。结果:在不同的阴道柱体上使用中心串联时,梁的有效衰减增大。当与直径35毫米的阴道筒一起使用时,300个角的中心串联产生最大的衰减,而与直径20毫米的阴道筒一起使用时,0º串联产生最小的衰减。结论:妇科肿瘤近距离放射治疗中,由于各种施放器的衰减,为正确估计靶及危险器官的剂量,应考虑实际剂量与治疗计划系统计算剂量的差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Dosimetric analysis of intracavitary brachytherapy applicators: a practical study.

Purpose: Intracavitary brachytherapy is one of the important methods of gynecological cancer treatment. The effect of attenuation is not considered in the dose calculation method released by the American Association of Physicists in Medicine (AAPM) Task Group No. 43 Report (TG-43). In this study, the effect of high-dose rate (HDR) brachytherapy applicators on dose distribution was measured using Gafchromic films and well-type ionization chamber.

Materials and methods: A plan created by the treatment planning system was first executed using a well-type ionization chamber with a water equivalent elasto-gel in place for charge collection. Again, same plan was executed using central tandems of various angulations with different diameters of vaginal cylinders and charge collection was measured. For in vitro dose measurements this plan was also executed on tandem and vaginal cylinder assembly with Gafchromic films fixed on the surface of vaginal cylinder.

Results: The results show that the central tandem when used with different vaginal cylinders resulted in increase in effective attenuation of the beam. The central tandem of 300 angulations when used with a 35-mm diameter vaginal cylinder results in maximum attenuation whereas the 0º tandem when used with 20-mm diameter vaginal cylinder results in least attenuation of the beam.

Conclusion: Due to the attenuation by various applicators used in brachytherapy for the treatment of gynecological cancers, it can be concluded that the difference between practical dose and the treatment planning system calculated dose should be considered for the correct estimation of the dose to the target and the organs-at-risk.

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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
24
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