致编辑:一种湿疹样,瘙痒性,非大疱性类天疱疮。

Kui Young Park, Moo Yeol Hyun, In Kwon Yeo, Seong Jun Seo, Chang Kwun Hong
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引用次数: 3

摘要

我们报告一个不寻常的大疱性类天疱疮(BP)的表现在一个57岁的妇女。她有一个月的瘙痒史,躯干和四肢有多个环形斑块,中心退行,没有相应的内部恶性肿瘤的迹象。组织病理学检查观察到嗜酸性海绵病,直接免疫荧光研究显示C3和IgG在基底膜区呈强线性染色。这个不寻常的病例表明,没有水疱并不一定排除BP的诊断,并支持先前的报道,即回旋性红斑可能是大疱性疾病的初始表现。
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Photoletter to the editor: An eczema-like, pruritic, nonbullous form of bullous pemphigoid.

We report a case with an unusual manifestation of bullous pemphigoid (BP) in a 57-year-old woman. She presented with a one-month history of pruritus and multiple annular patches with central regression on her trunk and extremities and there were no signs of corresponding internal malignancy. Eosinophilic spongiosis was observed in histopathologic examination and direct immunofluorescence studies revealed a strong linear staining pattern of the basement membrane zone with C3 and IgG. This unusual case indicates that a lack of blisters does not necessarily exclude a diagnosis of BP, and supports previous reports suggesting gyrate erythema can be an initial manifestation of bullous disease.

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