{"title":"k-组件建模的最小k核问题。","authors":"Cynthia I Wood, Illya V Hicks","doi":"10.1186/s13408-015-0027-4","DOIUrl":null,"url":null,"abstract":"<p><p>The concept of cell assembly was introduced by Hebb and formalized mathematically by Palm in the framework of graph theory. In the study of associative memory, a cell assembly is a group of neurons that are strongly connected and represent a \"concept\" of our knowledge. This group is wired in a specific manner such that only a fraction of its neurons will excite the entire assembly. We link the concept of cell assembly to the closure of a minimal k-core and study a particular type of cell assembly called k-assembly. The goal of this paper is to find all substructures within a network that must be excited in order to activate a k-assembly. Through numerical experiments, we confirm that fractions of these important subgroups overlap. To explore the problem, we present a backtracking algorithm to find all minimal k-cores of a given undirected graph, which belongs to the class of NP-hard problems. The proposed method is a modification of the Bron and Kerbosch algorithm for finding all cliques of an undirected graph. The results in the tested graphs offer insight in analyzing graph structure and help better understand how concepts are stored. </p>","PeriodicalId":54271,"journal":{"name":"Journal of Mathematical Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13408-015-0027-4","citationCount":"10","resultStr":"{\"title\":\"The Minimal k-Core Problem for Modeling k-Assemblies.\",\"authors\":\"Cynthia I Wood, Illya V Hicks\",\"doi\":\"10.1186/s13408-015-0027-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The concept of cell assembly was introduced by Hebb and formalized mathematically by Palm in the framework of graph theory. In the study of associative memory, a cell assembly is a group of neurons that are strongly connected and represent a \\\"concept\\\" of our knowledge. This group is wired in a specific manner such that only a fraction of its neurons will excite the entire assembly. We link the concept of cell assembly to the closure of a minimal k-core and study a particular type of cell assembly called k-assembly. The goal of this paper is to find all substructures within a network that must be excited in order to activate a k-assembly. Through numerical experiments, we confirm that fractions of these important subgroups overlap. To explore the problem, we present a backtracking algorithm to find all minimal k-cores of a given undirected graph, which belongs to the class of NP-hard problems. The proposed method is a modification of the Bron and Kerbosch algorithm for finding all cliques of an undirected graph. The results in the tested graphs offer insight in analyzing graph structure and help better understand how concepts are stored. </p>\",\"PeriodicalId\":54271,\"journal\":{\"name\":\"Journal of Mathematical Neuroscience\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2015-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s13408-015-0027-4\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Mathematical Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s13408-015-0027-4\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/7/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"Neuroscience\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mathematical Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13408-015-0027-4","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/7/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Neuroscience","Score":null,"Total":0}
The Minimal k-Core Problem for Modeling k-Assemblies.
The concept of cell assembly was introduced by Hebb and formalized mathematically by Palm in the framework of graph theory. In the study of associative memory, a cell assembly is a group of neurons that are strongly connected and represent a "concept" of our knowledge. This group is wired in a specific manner such that only a fraction of its neurons will excite the entire assembly. We link the concept of cell assembly to the closure of a minimal k-core and study a particular type of cell assembly called k-assembly. The goal of this paper is to find all substructures within a network that must be excited in order to activate a k-assembly. Through numerical experiments, we confirm that fractions of these important subgroups overlap. To explore the problem, we present a backtracking algorithm to find all minimal k-cores of a given undirected graph, which belongs to the class of NP-hard problems. The proposed method is a modification of the Bron and Kerbosch algorithm for finding all cliques of an undirected graph. The results in the tested graphs offer insight in analyzing graph structure and help better understand how concepts are stored.
期刊介绍:
The Journal of Mathematical Neuroscience (JMN) publishes research articles on the mathematical modeling and analysis of all areas of neuroscience, i.e., the study of the nervous system and its dysfunctions. The focus is on using mathematics as the primary tool for elucidating the fundamental mechanisms responsible for experimentally observed behaviours in neuroscience at all relevant scales, from the molecular world to that of cognition. The aim is to publish work that uses advanced mathematical techniques to illuminate these questions.
It publishes full length original papers, rapid communications and review articles. Papers that combine theoretical results supported by convincing numerical experiments are especially encouraged.
Papers that introduce and help develop those new pieces of mathematical theory which are likely to be relevant to future studies of the nervous system in general and the human brain in particular are also welcome.